Bernard Malissen
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Explore the profile of Bernard Malissen including associated specialties, affiliations and a list of published articles.
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273
Citations
16147
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Recent Articles
11.
Miallot R, Millet V, Roger A, Fenouil R, Tardivel C, Martin J, et al.
Life Sci Alliance
. 2023 Nov;
7(2).
PMID: 38030222
No abstract available.
12.
Miallot R, Millet V, Roger A, Fenouil R, Tardivel C, Martin J, et al.
Life Sci Alliance
. 2023 Oct;
6(12).
PMID: 37833072
The tumor microenvironment is a dynamic network of stromal, cancer, and immune cells that interact and compete for resources. We have previously identified the Vanin1 pathway as a tumor suppressor...
13.
Joachim A, Aussel R, Gelard L, Zhang F, Mori D, Gregoire C, et al.
J Exp Med
. 2023 Aug;
220(11).
PMID: 37624388
Mice with a loss-of-function mutation in the LAT adaptor (LatY136F) develop an autoimmune and type 2 inflammatory disorder called defective LAT signalosome pathology (DLSP). We analyzed via single-cell omics the...
14.
Demerle C, Gorvel L, Mello M, Pastor S, Degos C, Zarubica A, et al.
J Immunother Cancer
. 2023 May;
11(5).
PMID: 37230538
Background: Tumor necrosis factor superfamily member 14 (TNFRSF14)/herpes virus entry mediator (HVEM) is the ligand for B and T lymphocyte attenuator (BTLA) and CD160-negative immune co-signaling molecules as well as...
15.
Miallot R, Millet V, Groult Y, Modelska A, Crescence L, Roulland S, et al.
Life Sci Alliance
. 2023 Apr;
6(6).
PMID: 37024121
Aggressive tumors often display mitochondrial dysfunction. Upon oxidative stress, mitochondria undergo fission through OMA1-mediated cleavage of the fusion effector OPA1. In yeast, a redox-sensing switch participates in OMA1 activation. 3D...
16.
Ruminski K, Celis-Gutierrez J, Jarmuzynski N, Maturin E, Audebert S, Malissen M, et al.
Front Immunol
. 2023 Apr;
14:1139123.
PMID: 37006259
The propagation and diversification of signals downstream of the T cell receptor (TCR) involve several adaptor proteins that control the assembly of multimolecular signaling complexes (signalosomes). The global characterization of...
17.
Jneid B, Bochnakian A, Hoffmann C, Delisle F, Djacoto E, Sirven P, et al.
Sci Immunol
. 2023 Jan;
8(79):eabn6612.
PMID: 36638189
T cells that recognize tumor antigens are crucial for mounting antitumor immune responses. Induction of antitumor T cells in immunogenic tumors depends on STING, the intracellular innate immune receptor for...
18.
Arbulo-Echevarria M, Vico-Barranco I, Zhang F, Fernandez-Aguilar L, Chotomska M, Narbona-Sanchez I, et al.
Front Immunol
. 2022 Dec;
13:1054920.
PMID: 36569841
The LAT transmembrane adaptor is essential to transduce intracellular signals triggered by the TCR. Phosphorylation of its four C-terminal tyrosine residues (136, 175, 195, and 235 in mouse LAT) recruits...
19.
Levy R, Gothe F, Momenilandi M, Magg T, Materna M, Peters P, et al.
J Exp Med
. 2022 Dec;
220(2).
PMID: 36515678
Patients with inherited CARMIL2 or CD28 deficiency have defective T cell CD28 signaling, but their immunological and clinical phenotypes remain largely unknown. We show that only one of three CARMIL2...
20.
Rebejac J, Eme-Scolan E, Paroutaud L, Kharbouche S, Teleman M, Spinelli L, et al.
Immunity
. 2022 Nov;
55(11):2103-2117.e10.
PMID: 36323311
The surface of the central nervous system (CNS) is protected by the meninges, which contain a dense network of meningeal macrophages (MMs). Here, we examined the role of tissue-resident MM...