Bernard L Schneider
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Explore the profile of Bernard L Schneider including associated specialties, affiliations and a list of published articles.
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99
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4066
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Recent Articles
1.
Chauhan H, Carruthers N, Stemmer P, Schneider B, Moszczynska A
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684782
In recent years, methamphetamine (METH) misuse in the US has been rapidly increasing, and there is no FDA-approved pharmacotherapy for METH use disorder (MUD). In addition to being dependent on...
2.
Pacesa M, Nickel L, Schellhaas C, Schmidt J, Pyatova E, Kissling L, et al.
bioRxiv
. 2024 Dec;
PMID: 39677777
Protein-protein interactions (PPIs) are at the core of all key biological processes. However, the complexity of the structural features that determine PPIs makes their design challenging. We present BindCraft, an...
3.
Sutton E, Beauvais A, Yaworski R, De Repentigny Y, Reilly A, de Almeida M, et al.
EBioMedicine
. 2024 Nov;
110:105444.
PMID: 39515026
Background: The liver is a key metabolic organ, acting as a hub to metabolically connect various tissues. Spinal muscular atrophy (SMA) is a neuromuscular disorder whereby patients have an increased...
4.
Gaudry J, Aebi A, Valdes P, Schneider B
Methods Mol Biol
. 2024 Jun;
2810:55-74.
PMID: 38926272
Here, we describe methods for the production of adeno-associated viral (AAV) vectors by transient transfection of HEK293 cells grown in serum-free medium using orbital shaken bioreactors and the subsequent purification...
5.
Reilly A, Yaworski R, Beauvais A, Schneider B, Kothary R
Hum Mol Genet
. 2023 Dec;
33(6):510-519.
PMID: 38073249
Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease characterized by motor neuron loss and skeletal muscle atrophy. SMA is caused by the loss of the SMN1 gene and...
6.
Benlefki S, Younes R, Challuau D, Bernard-Marissal N, Hilaire C, Scamps F, et al.
Cell Mol Biol (Noisy-le-grand)
. 2023 Nov;
69(10):1-8.
PMID: 37953591
Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the most common motoneuron diseases affecting adults and infants, respectively. ALS and SMA are both characterized by the selective degeneration...
7.
Spataro S, Maco B, Escrig S, Jensen L, Polerecky L, Knott G, et al.
Acta Neuropathol Commun
. 2023 Sep;
11(1):157.
PMID: 37770947
In Parkinson's disease, pathogenic factors such as the intraneuronal accumulation of the protein α-synuclein affect key metabolic processes. New approaches are required to understand how metabolic dysregulations cause degeneration of...
8.
Squair J, Milano M, de Coucy A, Gautier M, Skinnider M, James N, et al.
Science
. 2023 Sep;
381(6664):1338-1345.
PMID: 37733871
Axon regeneration can be induced across anatomically complete spinal cord injury (SCI), but robust functional restoration has been elusive. Whether restoring neurological functions requires directed regeneration of axons from specific...
9.
Reimann R, Puzio M, Rosati A, Emmenegger M, Schneider B, Valdes P, et al.
Brain Pathol
. 2022 Nov;
33(2):e13130.
PMID: 36329611
The cellular prion protein PrP mediates the neurotoxicity of prions and other protein aggregates through poorly understood mechanisms. Antibody-derived ligands against the globular domain of PrP (GDL) can also initiate...
10.
Reilly A, Deguise M, Beauvais A, Yaworski R, Thebault S, Tessier D, et al.
Gene Ther
. 2022 Apr;
29(9):544-554.
PMID: 35462564
Spinal muscular atrophy (SMA) is a neuromuscular disease caused by loss of the SMN1 gene and low SMN protein levels. Although lower motor neurons are a primary target, there is...