Benoit Moindrot
Overview
Explore the profile of Benoit Moindrot including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
650
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Recent Articles
1.
Moindrot B, Imaizumi Y, Feil R
Biochem Soc Trans
. 2024 May;
52(3):973-986.
PMID: 38775198
Imprinted genes provide an attractive paradigm to unravel links between transcription and genome architecture. The parental allele-specific expression of these essential genes - which are clustered in chromosomal domains -...
2.
Farhadova S, Ghousein A, Charon F, Surcis C, Gomez-Velazques M, Roidor C, et al.
Nucleic Acids Res
. 2024 Apr;
52(11):6183-6200.
PMID: 38613389
The imprinted Dlk1-Dio3 domain comprises the developmental genes Dlk1 and Rtl1, which are silenced on the maternal chromosome in different cell types. On this parental chromosome, the domain's imprinting control...
3.
Moindrot B, Noordermeer D
Cell Genom
. 2023 Feb;
2(4):100121.
PMID: 36776526
Hi-C is a powerful technology for exploring 3D genome organization on a genome-wide scale, yet it can be financially and computationally challenging. In a recent issue of , Wei et ...
4.
Moniot-Perron L, Moindrot B, Manceau L, Edouard J, Jaszczyszyn Y, Gilardi-Hebenstreit P, et al.
Cell Rep
. 2023 Jan;
42(1):111967.
PMID: 36640345
Hox genes encode transcription factors that specify segmental identities along the anteroposterior body axis. These genes are organized in clusters, where their order corresponds to their activity along the body...
5.
Miranda M, Noordermeer D, Moindrot B
Methods Mol Biol
. 2022 Jul;
2532:15-33.
PMID: 35867243
Chromosome conformation capture techniques are a set of methods used to determine 3D genome organization through the capture and identification of physical contacts between pairs of genomic loci. Among them,...
6.
Coker H, Wei G, Moindrot B, Mohammed S, Nesterova T, Brockdorff N
Wellcome Open Res
. 2020 Apr;
5:31.
PMID: 32258426
: X chromosome inactivation in mammals is regulated by the non-coding (nc) RNA, Xist, which represses the chromosome from which it is transcribed. High levels of the N6-methyladenosine (m6A) RNA...
7.
Lleres D, Moindrot B, Pathak R, Piras V, Matelot M, Pignard B, et al.
Genome Biol
. 2019 Dec;
20(1):272.
PMID: 31831055
Background: Genomic imprinting is essential for mammalian development and provides a unique paradigm to explore intra-cellular differences in chromatin configuration. So far, the detailed allele-specific chromatin organization of imprinted gene...
8.
Nesterova T, Wei G, Coker H, Pintacuda G, Bowness J, Zhang T, et al.
Nat Commun
. 2019 Jul;
10(1):3129.
PMID: 31311937
Xist RNA, the master regulator of X chromosome inactivation, acts in cis to induce chromosome-wide silencing. Whilst recent studies have defined candidate silencing factors, their relative contribution to repressing different...
9.
Moindrot B, Brockdorff N
Methods Mol Biol
. 2018 Sep;
1861:19-36.
PMID: 30218356
In mammals, a dosage compensation mechanism exists to equalize gene expression levels between male and female. This process is initiated by Xist RNA, a long noncoding RNA that mediates the...
10.
Pintacuda G, Wei G, Roustan C, Kirmizitas B, Solcan N, Cerase A, et al.
Mol Cell
. 2017 Dec;
68(5):955-969.e10.
PMID: 29220657
The Polycomb-repressive complexes PRC1 and PRC2 play a key role in chromosome silencing induced by the non-coding RNA Xist. Polycomb recruitment is initiated by the PCGF3/5-PRC1 complex, which catalyzes chromosome-wide...