Benoit Mailhot
Overview
Explore the profile of Benoit Mailhot including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
629
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0
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Recent Articles
1.
Fazazi M, Doss P, Pereira R, Fudge N, Regmi A, Joly-Beauparlant C, et al.
Nat Commun
. 2024 Jun;
15(1):5404.
PMID: 38926356
B cells and T cells collaborate in multiple sclerosis (MS) pathogenesis. IgH mice possess a B cell repertoire skewed to recognize myelin oligodendrocyte glycoprotein (MOG). Here, we show that upon...
2.
Bretheau F, Castellanos-Molina A, Belanger D, Kusik M, Mailhot B, Boisvert A, et al.
Nat Commun
. 2022 Oct;
13(1):5786.
PMID: 36184639
Spinal cord injury (SCI) triggers neuroinflammation, and subsequently secondary degeneration and oligodendrocyte (OL) death. We report that the alarmin interleukin (IL)-1α is produced by damaged microglia after SCI. Intra-cisterna magna...
3.
Girard A, Dugas M, Lepine J, Carnovale V, Jalbert L, Turmel A, et al.
J Eval Clin Pract
. 2022 Jul;
29(1):233-249.
PMID: 35796093
Rationale: Moving towards high quality primary health care, involving family physicians in primary care research becomes an essential prerequisite to ensures a better adoption and routinization of patient-centred, evidence-based practices....
4.
Melki I, Allaeys I, Tessandier N, Mailhot B, Cloutier N, Campbell R, et al.
Blood
. 2020 Dec;
136(25):2933-2945.
PMID: 33331924
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease characterized by deposits of immune complexes (ICs) in organs and tissues. The expression of FcγRIIA by human platelets, which is their...
5.
Mailhot B, Christin M, Tessandier N, Sotoudeh C, Bretheau F, Turmel R, et al.
J Exp Med
. 2020 Jun;
217(9).
PMID: 32573694
Chronic pain is a major comorbidity of chronic inflammatory diseases. Here, we report that the cytokine IL-1β, which is abundantly produced during multiple sclerosis (MS), arthritis (RA), and osteoarthritis (OA)...
6.
Yeola A, Doss P, Baillargeon J, Akbar I, Mailhot B, Balood M, et al.
Front Immunol
. 2020 Feb;
10:3115.
PMID: 32010149
The T cell response to central nervous system (CNS) antigen in experimental autoimmune encephalomyelitis (EAE) permits one to model the immune aspects of multiple sclerosis. 1C6 transgenic mice on the...
7.
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury
Bellver-Landete V, Bretheau F, Mailhot B, Vallieres N, Lessard M, Janelle M, et al.
Nat Commun
. 2019 Feb;
10(1):518.
PMID: 30705270
The role of microglia in spinal cord injury (SCI) remains poorly understood and is often confused with the response of macrophages. Here, we use specific transgenic mouse lines and depleting...
8.
Cloutier N, Allaeys I, Marcoux G, Machlus K, Mailhot B, Zufferey A, et al.
Proc Natl Acad Sci U S A
. 2018 Feb;
115(7):E1550-E1559.
PMID: 29386381
There is a growing appreciation for the contribution of platelets to immunity; however, our knowledge mostly relies on platelet functions associated with vascular injury and the prevention of bleeding. Circulating...
9.
Pare A, Mailhot B, Levesque S, Juzwik C, Doss P, Lecuyer M, et al.
Proc Natl Acad Sci U S A
. 2018 Jan;
115(6):E1194-E1203.
PMID: 29358392
Molecular interventions that limit pathogenic CNS inflammation are used to treat autoimmune conditions such as multiple sclerosis (MS). Remarkably, IL-1β-knockout mice are highly resistant to experimental autoimmune encephalomyelitis (EAE), an...
10.
Pare A, Mailhot B, Levesque S, Lacroix S
Brain Behav Immun
. 2016 Jul;
62:1-8.
PMID: 27432634
Multiple sclerosis (MS) is an autoimmune disease that affects hundreds of thousands of people worldwide. Given the autoimmune nature of the disease, a large part of the research has focused...