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Benjamin Parks

Explore the profile of Benjamin Parks including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 380
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Recent Articles
1.
Gamble N, Bradu A, Caldwell J, McKeever J, Bolonduro O, Ermis E, et al.
Nat Immunol . 2024 May; 25(6):1123. PMID: 38755325
No abstract available.
2.
Gamble N, Bradu A, Caldwell J, McKeever J, Bolonduro O, Ermis E, et al.
Nat Immunol . 2024 Apr; 25(5):860-872. PMID: 38632339
Adaptive immunity relies on specialized effector functions elicited by lymphocytes, yet how antigen recognition activates appropriate effector responses through nonspecific signaling intermediates is unclear. Here we examined the role of...
3.
Chen A, Parks B, Kathiria A, Ober-Reynolds B, Goronzy J, Greenleaf W
Nat Methods . 2022 May; 19(5):547-553. PMID: 35501385
In this work, we describe NEAT-seq (sequencing of nuclear protein epitope abundance, chromatin accessibility and the transcriptome in single cells), enabling interrogation of regulatory mechanisms spanning the central dogma. We...
4.
Wilk A, Lee M, Wei B, Parks B, Pi R, Martinez-Colon G, et al.
J Exp Med . 2021 Jun; 218(8). PMID: 34128959
Our understanding of protective versus pathological immune responses to SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of patients at the extremes of the...
5.
Granja J, Klemm S, McGinnis L, Kathiria A, Mezger A, Corces M, et al.
Nat Biotechnol . 2019 Dec; 37(12):1458-1465. PMID: 31792411
Identifying the causes of human diseases requires deconvolution of abnormal molecular phenotypes spanning DNA accessibility, gene expression and protein abundance. We present a single-cell framework that integrates highly multiplexed protein...