Benjamin N Bimber
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Explore the profile of Benjamin N Bimber including associated specialties, affiliations and a list of published articles.
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48
Citations
1481
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Recent Articles
1.
Haese N, Smith H, Onwuzu K, Kreklywich C, Smith J, Denton M, et al.
Front Virol
. 2025 Feb;
1.
PMID: 40012721
Zika virus (ZIKV) is an arthropod-borne Flavivirus that can also be transmitted vertically from infected mother to fetus. Infection of the fetus during pregnancy can lead to congenital malformations and...
2.
Rust L, Wettengel J, Biswas S, Ryu J, Piekarski N, Yusova S, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(7):e2413771122.
PMID: 39937851
Hepatitis B virus (HBV) poses a significant global health challenge, necessitating the urgent development of curative therapeutics. However, this progress is impeded by the lack of robust, immunocompetent preclinical animal...
3.
Malouli D, Taher H, Mansouri M, Iyer R, Reed J, Papen C, et al.
Sci Immunol
. 2024 Oct;
9(100):eadp5216.
PMID: 39392895
Rhesus cytomegalovirus (RhCMV) vectors elicit major histocompatibility complex (MHC)-E-restricted CD8 T cells that stringently control simian immunodeficiency virus (SIV) in rhesus macaques. These responses require deletion of eight RhCMV chemokine-like...
4.
Bimber B, Sunshine J, McElfresh G, Reed J, Pathak R, Bateman K, et al.
Front Immunol
. 2024 Aug;
15:1444621.
PMID: 39170621
Simian immunodeficiency virus (SIV) vaccines based upon 68-1 Rhesus Cytomegalovirus (RhCMV) vectors show remarkable protection against pathogenic SIVmac239 challenge. Across multiple independent rhesus macaque (RM) challenge studies, nearly 60% of...
5.
Deycmar S, Johnson B, Ray K, Schaaf G, Ryan D, Cullin C, et al.
J Transl Med
. 2024 Mar;
22(1):292.
PMID: 38504345
Background: Naturally occurring colorectal cancers (CRC) in rhesus macaques share many features with their human counterparts and are useful models for cancer immunotherapy; but mechanistic data are lacking regarding the...
6.
Streblow D, Hirsch A, Stanton J, Lewis A, Colgin L, Hessell A, et al.
Nat Commun
. 2023 Nov;
14(1):7062.
PMID: 37923717
Passively administered monoclonal antibodies (mAbs) given before or after viral infection can prevent or blunt disease. Here, we examine the efficacy of aerosol mAb delivery to prevent infection and disease...
7.
Wu H, Busman-Sahay K, Weber W, Waytashek C, Boyle C, Bateman K, et al.
Immunity
. 2023 May;
56(7):1649-1663.e5.
PMID: 37236188
Allogeneic hematopoietic stem cell transplantation (alloHSCT) from donors lacking C-C chemokine receptor 5 (CCR5) can cure HIV, yet mechanisms remain speculative. To define how alloHSCT mediates HIV cure, we performed...
8.
Wettengel J, Hansen-Palmus L, Yusova S, Rust L, Biswas S, Carson J, et al.
Int J Mol Sci
. 2023 May;
24(9).
PMID: 37175977
CRISPR/Cas systems are some of the most promising tools for therapeutic genome editing. The use of these systems is contingent on the optimal designs of guides and homology-directed repair (HDR)...
9.
Diesh C, Stevens G, Xie P, De Jesus Martinez T, Hershberg E, Leung A, et al.
Genome Biol
. 2023 Apr;
24(1):74.
PMID: 37069644
We present JBrowse 2, a general-purpose genome annotation browser offering enhanced visualization of complex structural variation and evolutionary relationships. It retains core features of JBrowse while adding new views for...
10.
Biswas S, Rust L, Wettengel J, Yusova S, Fischer M, Carson J, et al.
Nat Commun
. 2022 May;
13(1):2995.
PMID: 35637225
Hepatitis B virus has infected a third of the world's population, and 296 million people are living with chronic infection. Chronic infection leads to progressive liver disease, including hepatocellular carcinoma...