David H OConnor
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Explore the profile of David H OConnor including associated specialties, affiliations and a list of published articles.
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262
Citations
8726
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Recent Articles
1.
Li A, Coffey L, Mohr E, Raper J, Chahroudi A, Ausderau K, et al.
Lancet Microbe
. 2025 Mar;
:101030.
PMID: 40024258
Zika virus, a mosquito-transmitted orthoflavivirus, has become a pathogen of global health concern ever since the virus caused an epidemic in Brazil in 2015 associated with approximately 700 000 laboratory-confirmed...
2.
Stachler E, Gnirke A, McMahon K, Gomez M, Stenson L, Guevara-Reyes C, et al.
medRxiv
. 2024 Dec;
PMID: 39677482
Highly Pathogenic Avian Influenza strain H5N1 has caused a multi-state outbreak among US dairy cattle, spreading across 15 states and infecting hundreds of herds since its onset. We rapidly developed...
3.
Kent S, Li S, Amarasena T, Reynaldi A, Lee W, Leeming M, et al.
ACS Nano
. 2024 Sep;
18(39):27077-27089.
PMID: 39298422
Lipid nanoparticle mRNA vaccines are an exciting but emerging technology used in humans. There is limited understanding of the factors that influence their biodistribution and immunogenicity. Antibodies to poly(ethylene glycol)...
4.
Nennig K, Murthy S, Maloney S, Shaw T, Sharobim M, Matkovic E, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012436.
PMID: 39196893
Viruses capable of causing persistent infection have developed sophisticated mechanisms for evading host immunity, and understanding these processes can reveal novel features of the host immune system. One such virus,...
5.
Arkin L, Costa-da-Silva A, Frere J, Ng A, Sharma R, Moon J, et al.
iScience
. 2024 Aug;
27(8):110525.
PMID: 39156641
Elevated pernio incidence was observed during the COVID-19 pandemic. This prospective study enrolled subjects with pandemic-associated pernio in Wisconsin and Switzerland. Because pernio is a cutaneous manifestation of the interferonopathies,...
6.
Wang J, Wang M, Moshiri A, Harris R, Raveendran M, Nguyen T, et al.
Nat Commun
. 2024 Jul;
15(1):5658.
PMID: 38969634
Understanding and treating human diseases require valid animal models. Leveraging the genetic diversity in rhesus macaque populations across eight primate centers in the United States, we conduct targeted-sequencing on 1845...
7.
Krabbe N, Mitzey A, Bhattacharya S, Razo E, Zeng X, Bekiares N, et al.
bioRxiv
. 2024 Jun;
PMID: 38853987
One Sentence Summary: Clade IIb Mpox virus infection of pregnant rhesus macaques results in vertical transmission from mother to fetus and adverse pregnancy outcomes.
8.
Prall T, Karl J, Varghese J, Baker D, Minor N, Raveendran M, et al.
J Immunol
. 2024 Apr;
212(11):1754-1765.
PMID: 38639635
Mauritian-origin cynomolgus macaques (MCMs) serve as a powerful nonhuman primate model in biomedical research due to their unique genetic homogeneity, which simplifies experimental designs. Despite their extensive use, a comprehensive...
9.
Shaw T, Dettle S, Mejia A, Hayes J, Simmons H, Basu P, et al.
Emerg Infect Dis
. 2024 Mar;
30(4):721-731.
PMID: 38526136
Genetically diverse simian arteriviruses (simarteriviruses) naturally infect geographically and phylogenetically diverse monkeys, and cross-species transmission and emergence are of considerable concern. Characterization of most simarteriviruses beyond sequence analysis has not...
10.
Shafer M, Bobholz M, Vuyk W, Gregory D, Roguet A, Haddock Soto L, et al.
Lancet Microbe
. 2024 Mar;
5(4):e335-e344.
PMID: 38484748
Background: The origin of novel SARS-CoV-2 spike sequences found in wastewater, without corresponding detection in clinical specimens, remains unclear. We sought to determine the origin of one such cryptic wastewater...