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Benjamin J Wilkins

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Articles 57
Citations 2303
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Recent Articles
11.
Danan C, Naughton K, Hayer K, Vellappan S, McMillan E, Zhou Y, et al.
bioRxiv . 2023 Apr; PMID: 37066277
Intestinal epithelial transit amplifying cells are essential stem progenitors required for intestinal homeostasis, but their rapid proliferation renders them vulnerable to DNA damage from radiation and chemotherapy. Despite their critical...
12.
Martinelli M, Aguilar G, Lee D, Kromer A, Nguyen N, Wilkins B, et al.
iScience . 2023 Jan; 26(1):105860. PMID: 36632062
The RNA-binding protein Pcbp2 is widely expressed in the innate and adaptive immune systems and is essential for mouse development. To determine whether Pcbp2 is required for CD4 T cell...
13.
Lynch K, Benitez A, Godwin B, Klein J, Savant D, Wilkins B, et al.
Clin Transl Gastroenterol . 2023 Jan; 14(4):e00564. PMID: 36603149
Introduction: Inflammation in eosinophilic esophagitis (EoE) often leads to esophageal strictures. Evaluating esophageal narrowing is clinically challenging. We evaluated esophageal distensibility as related to disease activity, fibrosis, and dysphagia. Methods:...
14.
Park S, Kang S, Paek J, Georgescu A, Chang J, Yi A, et al.
Nat Methods . 2022 Oct; 19(11):1449-1460. PMID: 36280722
Here, we introduce a facile, scalable engineering approach to enable long-term development and maturation of organoids. We have redesigned the configuration of conventional organoid culture to develop a platform that...
15.
Gonzalez I, Linn R, Wilkins B
Pediatr Dev Pathol . 2022 Aug; 25(6):661-667. PMID: 36031872
We present a case of solid-tubulocystic variant of intrahepatic cholangiocarcinoma (also called cholangioblastic variant of intrahepatic cholangiocarcinoma) in a 15-year-old girl, the youngest patient reported to date. The tumor was...
16.
Muir A, Ackerman S, Pan Z, Benitez A, Burger C, Spergel J, et al.
J Allergy Clin Immunol . 2022 Apr; 150(3):649-656.e5. PMID: 35405206
Background: Esophageal remodeling is a factor in disease progression and symptom severity for patients with eosinophilic esophagitis (EoE). Remodeling can begin early in children, resulting in stricture and food impaction....
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Siska P, Jiao J, Matos C, Singer K, Berger R, Dettmer K, et al.
EBioMedicine . 2021 Dec; 74:103734. PMID: 34875457
Background: L-kynurenine is a tryptophan-derived immunosuppressive metabolite and precursor to neurotoxic anthranilate and quinolinate. We evaluated the stereoisomer D-kynurenine as an immunosuppressive therapeutic which is hypothesized to produce less neurotoxic...
19.
Alharbi H, Priestley J, Wilkins B, Ganetzky R
Clin Liver Dis (Hoboken) . 2021 Nov; 18(5):243-250. PMID: 34840726
No abstract available.
20.
Wilkins B, Kelsen J, Conrad M
Adv Anat Pathol . 2021 Nov; 29(1):62-70. PMID: 34813528
Very early-onset inflammatory bowel disease (VEO-IBD), IBD diagnosed in children younger than 6 years old, is phenotypically and genetically distinct from older onset IBD. Monogenic and digenic causative defects, particularly...