Michael Pack
Overview
Explore the profile of Michael Pack including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
1468
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Recent Articles
1.
Kaestner K, Pack M
Cell Mol Gastroenterol Hepatol
. 2024 Apr;
17(6):1063.
PMID: 38636550
No abstract available.
2.
Liu X, Jones W, Quesnel-Vallieres M, Devadiga S, Lorent K, Valvezan A, et al.
J Dev Biol
. 2023 Jul;
11(3).
PMID: 37489330
Neural crest (NC) is a unique vertebrate cell type arising from the border of the neural plate and epidermis that gives rise to diverse tissues along the entire body axis....
3.
Kaestner K, Pack M
Cell Mol Gastroenterol Hepatol
. 2021 Nov;
12(5):1873-1874.
PMID: 34772482
No abstract available.
4.
5.
Zhao X, Lorent K, Escobar-Zarate D, Rajagopalan R, Loomes K, Gillespie K, et al.
Gastroenterology
. 2020 Jun;
159(3):1068-1084.e2.
PMID: 32505743
Background & Aims: Extrahepatic biliary atresia (BA) is a pediatric liver disease with no approved medical therapy. Recent studies using human samples and experimental modeling suggest that glutathione redox metabolism...
6.
McKinstry-Wu A, Wasilczuk A, Harrison B, Bedell V, Sridharan M, Breig J, et al.
Elife
. 2019 Dec;
8.
PMID: 31793434
Traditionally, drug dosing is based on a concentration-response relationship estimated in a population. Yet, in specific individuals, decisions based on the population-level effects frequently result in over or under-dosing. Here,...
7.
Kaestner K, Pack M
Cell Mol Gastroenterol Hepatol
. 2019 Sep;
8(3):527.
PMID: 31518556
No abstract available.
8.
Estrada M, Zhao X, Lorent K, Kriegermeier A, Nagao S, Berritt S, et al.
ACS Med Chem Lett
. 2018 Jan;
9(1):61-64.
PMID: 29348813
We report the first synthesis of the plant isoflavonoid biliatresone. The convergent synthesis has been applied to the synthesis of several analogs, which have facilitated the first structure-activity relationship study...
9.
Kieckhaefer J, Lukovac S, Ye D, Lee D, Beetler D, Pack M, et al.
Cell Mol Gastroenterol Hepatol
. 2017 Jan;
2(6):783-795.
PMID: 28090567
Background & Aims: The continuously self-renewing mammalian intestinal epithelium, with high cellular turnover, depends on adequate protein synthesis for its proliferative capacity. RNA polymerase III activity is closely related to...
10.
Zhao X, Lorent K, Wilkins B, Marchione D, Gillespie K, Waisbourd-Zinman O, et al.
Hepatology
. 2016 Apr;
64(3):894-907.
PMID: 27102575
Unlabelled: Biliatresone is an electrophilic isoflavone isolated from Dysphania species plants that has been causatively linked to naturally occurring outbreaks of a biliary atresia (BA)-like disease in livestock. Biliatresone has...