Benjamin G Vincent
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Explore the profile of Benjamin G Vincent including associated specialties, affiliations and a list of published articles.
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97
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7623
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Recent Articles
11.
Vincent B, File D, McKinnon K, Moore D, Frelinger J, Collins E, et al.
J Immunol
. 2023 May;
211(2):219-228.
PMID: 37204246
Previous work from our group and others has shown that patients with breast cancer can generate a T cell response against specific human epidermal growth factor 2 (HER2) epitopes. In...
12.
Vensko S, Olsen K, Bortone D, Smith C, Chai S, Beckabir W, et al.
Bioinformatics
. 2023 May;
39(6).
PMID: 37184881
Motivation: Elimination of cancer cells by T cells is a critical mechanism of anti-tumor immunity and cancer immunotherapy response. T cells recognize cancer cells by engagement of T cell receptors...
13.
Qi T, Vincent B, Cao Y
PLoS Comput Biol
. 2023 Apr;
19(4):e1010976.
PMID: 37083574
Predator-prey theory is commonly used to describe tumor growth in the presence of selective pressure from the adaptive immune system. These interactions are mediated by the tumor immunopeptidome (what the...
14.
Routh E, Woodcock M, Beckabir W, Vensko S, Serody J, Vincent B
J Immunother Cancer
. 2023 Mar;
11(3).
PMID: 36882226
The role of B cells in antitumor immunity is becoming increasingly appreciated, as B cell populations have been associated with response to immune checkpoint blockade (ICB) in patients with breast...
15.
Olsen K, Jadi O, Dexheimer S, Bortone D, Vensko S, Bennett S, et al.
Blood Adv
. 2022 Dec;
7(9):1635-1649.
PMID: 36477467
T-cell responses to minor histocompatibility antigens (mHAs) mediate graft-versus-leukemia (GVL) effects and graft-versus-host disease (GVHD) in allogeneic hematopoietic cell transplantation. Therapies that boost T-cell responses improve allogeneic hematopoietic cell transplant...
16.
Damrauer J, Beckabir W, Klomp J, Zhou M, Plimack E, Galsky M, et al.
Nat Commun
. 2022 Nov;
13(1):6658.
PMID: 36333289
Urothelial Cancer - Genomic Analysis to Improve Patient Outcomes and Research (NCT02643043), UC-GENOME, is a genomic analysis and biospecimen repository study in 218 patients with metastatic urothelial carcinoma. Here we...
17.
Li S, Mirlekar B, Johnson B, Brickey W, Wrobel J, Yang N, et al.
Nature
. 2022 Oct;
610(7931):373-380.
PMID: 36198789
An immunosuppressive tumour microenvironment is a major obstacle in the control of pancreatic and other solid cancers. Agonists of the stimulator of interferon genes (STING) protein trigger inflammatory innate immune...
18.
Mirlekar B, Wang Y, Li S, Zhou M, Entwistle S, De Buysscher T, et al.
Cell Rep Med
. 2022 Sep;
3(9):100744.
PMID: 36099917
Plasma cell responses are associated with anti-tumor immunity and favorable response to immunotherapy. B cells can amplify anti-tumor immune responses through antibody production; yet B cells in patients and tumor-bearing...
19.
Routh E, Van Swearingen A, Sambade M, Vensko S, McClure M, Woodcock M, et al.
Front Oncol
. 2022 Aug;
12:818693.
PMID: 35992833
Background: Triple negative breast cancer (TNBC) is an aggressive variant of breast cancer that lacks the expression of estrogen and progesterone receptors (ER and PR) and HER2. Nearly 50% of...
20.
Chai S, Smith C, Kochar T, Hunsucker S, Beck W, Olsen K, et al.
Bioinform Adv
. 2022 Jun;
2(1):vbac032.
PMID: 35669345
Motivation: Splice variant neoantigens are a potential source of tumor-specific antigen (TSA) that are shared between patients in a variety of cancers, including acute myeloid leukemia. Current tools for genomic...