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Benjamin F Miller

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Articles 213
Citations 4122
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Recent Articles
1.
Sklivas A, Sklivas A, Hettinger Z, Hettinger Z, Rose S, Rose S, et al.
J Appl Physiol (1985) . 2025 Jan; 138(3):652-665. PMID: 39884317
The purpose of this study was to investigate the ability of mechanotherapy to enhance recovery or prevent loss of muscle size with disuse in female rats. Female F344/BN rats were...
2.
Borowik A, Murach K, Miller B
Biochem Soc Trans . 2024 Dec; 52(6):1-14. PMID: 39700019
Skeletal muscle cells (myofibers) require multiple nuclei to support a cytoplasmic volume that is larger than other mononuclear cell types. It is dogmatic that mammalian resident myonuclei rely on stem...
3.
Zarzycka W, Kobak K, King C, Peelor 3rd F, Miller B, Chiao Y
Geroscience . 2024 Oct; PMID: 39379739
The mechanistic target of rapamycin complex 1 (mTORC1) has a major impact on aging by regulation of proteostasis. It is well established that mTORC1 signaling is hyperactivated with aging and...
4.
Musci R, Fuqua J, Peelor 3rd F, Nguyen H, Richardson A, Choi S, et al.
Geroscience . 2024 Sep; 47(1):851-862. PMID: 39312152
Mitochondrial genomic integrity is a key element of physiological processes and health. Changes in the half-life of the mitochondrial genome are implicated in the generation and accumulation of age-induced mitochondrial...
5.
Kemna R, Kueck P, Blankenship A, John C, Johnson C, Green Z, et al.
Contemp Clin Trials . 2024 Sep; 146:107682. PMID: 39236780
Background: There is evidence that chronic exercise can benefit the brain, but the effects vary markedly between studies. One potential mechanism for exercise-related benefit is the increase in systemic lactate...
6.
Kim H, Ranjit R, Claflin D, Georgescu C, Wren J, Brooks S, et al.
Aging Cell . 2024 Sep; 23(12):e14323. PMID: 39223708
Sarcopenia, the progressive loss of muscle mass and function, universally affects older adults and is closely associated with frailty and reduced quality of life. Despite the inevitable consequences of sarcopenia...
7.
Deberneh H, Taylor M, Borowik A, Miyagi M, Miller B, Sadygov R
J Am Soc Mass Spectrom . 2024 Jul; 35(8):1826-1837. PMID: 39057601
Labeling with deuterium oxide (DO) has emerged as one of the preferred approaches for measuring the synthesis of individual proteins in vivo. In these experiments, the synthesis rates of proteins...
8.
Kobak K, Batushansky A, Jopkiewicz A, Peelor 3rd F, Kinter M, Miller B, et al.
Osteoarthr Cartil Open . 2024 Jul; 6(3):100495. PMID: 39040627
Objective: To identify factors contributing to sex-differences in OA risk by evaluating the short-term effect of high-fat (HF) diet on sex-specific changes in cartilage cell proliferation, ribosomal biogenesis, and targeted...
9.
Bubak M, Davidyan A, OReilly C, Mondal S, Keast J, Doidge S, et al.
Aging Cell . 2024 Jun; 23(9):e14235. PMID: 38923664
The rationale for the use of metformin as a treatment to slow aging was largely based on data collected from metabolically unhealthy individuals. For healthspan extension metformin will also be...
10.
Zarzycka W, Kobak K, King C, Peelor F, Miller B, Chiao Y
bioRxiv . 2024 May; PMID: 38798509
The mechanistic target of rapamycin complex 1 (mTORC1) has a major impact on aging by regulation of proteostasis. It is well established that mTORC1 signaling is hyperactivated with aging and...