Agnieszka K Borowik
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Explore the profile of Agnieszka K Borowik including associated specialties, affiliations and a list of published articles.
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16
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69
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Recent Articles
1.
Borowik A, Murach K, Miller B
Biochem Soc Trans
. 2024 Dec;
52(6):1-14.
PMID: 39700019
Skeletal muscle cells (myofibers) require multiple nuclei to support a cytoplasmic volume that is larger than other mononuclear cell types. It is dogmatic that mammalian resident myonuclei rely on stem...
2.
Fuqua J, Mesquita P, Taylor M, Borowik A
J Physiol
. 2024 Sep;
602(20):5149-5150.
PMID: 39222396
No abstract available.
3.
Deberneh H, Taylor M, Borowik A, Miyagi M, Miller B, Sadygov R
J Am Soc Mass Spectrom
. 2024 Jul;
35(8):1826-1837.
PMID: 39057601
Labeling with deuterium oxide (DO) has emerged as one of the preferred approaches for measuring the synthesis of individual proteins in vivo. In these experiments, the synthesis rates of proteins...
4.
Bubak M, Davidyan A, OReilly C, Mondal S, Keast J, Doidge S, et al.
Aging Cell
. 2024 Jun;
23(9):e14235.
PMID: 38923664
The rationale for the use of metformin as a treatment to slow aging was largely based on data collected from metabolically unhealthy individuals. For healthspan extension metformin will also be...
5.
Bubak M, Davidyan A, OReilly C, Mondal S, Keast J, Doidge S, et al.
bioRxiv
. 2024 Mar;
PMID: 38496648
The rationale for the use of metformin as a treatment to slow aging was largely based on data collected from metabolically unhealthy individuals. For healthspan extension metformin will also be...
6.
Borowik A, Lawrence M, Peelor 3rd F, Piekarz K, Crosswhite A, Richardson A, et al.
Geroscience
. 2024 Jan;
46(3):3219-3233.
PMID: 38233728
Oxidative stress is associated with tissue dysfunctions that can lead to reduced health. Prior work has shown that oxidative stress contributes to both muscle atrophy and cellular senescence, which is...
7.
Bubak M, Mann S, Borowik A, Pranay A, Batushansky A, de Sousa Neto I, et al.
Am J Physiol Endocrinol Metab
. 2024 Jan;
326(3):E226-E244.
PMID: 38197793
17α-estradiol (17α-E2) is a naturally occurring nonfeminizing diastereomer of 17β-estradiol that has life span-extending effects in rodent models. To date, studies of the systemic and tissue-specific benefits of 17α-E2 have...
8.
Batterson P, McGowan E, Borowik A, Kinter M, Miller B, Newsom S, et al.
Physiol Rep
. 2023 Oct;
11(20):e15840.
PMID: 37857571
High-fat diet (HFD) and exercise remodel skeletal muscle mitochondria. The electron transfer flavoproteins (ETF) transfer reducing equivalents from β-oxidation into the electron transfer system. Exercise may stimulate the synthesis of...
9.
Fuqua J, Lawrence M, Hettinger Z, Borowik A, Brecheen P, Szczygiel M, et al.
J Cachexia Sarcopenia Muscle
. 2023 Jul;
14(5):2076-2089.
PMID: 37448295
Background: Skeletal muscle mass and strength diminish during periods of disuse but recover upon return to weight bearing in healthy adults but are incomplete in old muscle. Efforts to improve...
10.
Bubak M, Mann S, Borowik A, Pranay A, Batushansky A, Ali Mondal S, et al.
bioRxiv
. 2023 Jul;
PMID: 37398463
Skeletal muscle has a central role in maintaining metabolic homeostasis. 17α-estradiol (17α-E2), a naturally-occurring non-feminizing diastereomer of 17β-estradiol that demonstrates efficacy for improving metabolic outcomes in male, but not female,...