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Benjamin F Miller

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Articles 213
Citations 4122
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Recent Articles
11.
Milan M, Brown J, OReilly C, Bubak M, Negri S, Balasubramanian P, et al.
Redox Biol . 2024 May; 73:103189. PMID: 38788541
Age-related endothelial dysfunction is a pivotal factor in the development of cardiovascular diseases, stemming, at least in part, from mitochondrial dysfunction and a consequential increase in oxidative stress. These alterations...
12.
Bubak M, Davidyan A, OReilly C, Mondal S, Keast J, Doidge S, et al.
bioRxiv . 2024 Mar; PMID: 38496648
The rationale for the use of metformin as a treatment to slow aging was largely based on data collected from metabolically unhealthy individuals. For healthspan extension metformin will also be...
13.
Larson K, Jayakrishnan D, Soto Sauza K, Goodson M, Chaffin A, Davidyan A, et al.
Endocrinology . 2024 Jan; 165(3. PMID: 38244215
Fibroblast growth factor-21 (FGF21) is an intercellular signaling molecule secreted by metabolic organs, including skeletal muscle, in response to intracellular stress. FGF21 crosses the blood-brain barrier and acts via the...
14.
Borowik A, Lawrence M, Peelor 3rd F, Piekarz K, Crosswhite A, Richardson A, et al.
Geroscience . 2024 Jan; 46(3):3219-3233. PMID: 38233728
Oxidative stress is associated with tissue dysfunctions that can lead to reduced health. Prior work has shown that oxidative stress contributes to both muscle atrophy and cellular senescence, which is...
15.
Bubak M, Mann S, Borowik A, Pranay A, Batushansky A, de Sousa Neto I, et al.
Am J Physiol Endocrinol Metab . 2024 Jan; 326(3):E226-E244. PMID: 38197793
17α-estradiol (17α-E2) is a naturally occurring nonfeminizing diastereomer of 17β-estradiol that has life span-extending effects in rodent models. To date, studies of the systemic and tissue-specific benefits of 17α-E2 have...
16.
OReilly C, Bodine S, Miller B
J Physiol . 2023 Dec; 603(1):7-15. PMID: 38051758
No abstract available.
17.
Damian A, Miller B, Gallo J
Front Psychiatry . 2023 Nov; 14:1303277. PMID: 38025436
No abstract available.
18.
Hulett N, Knaub L, Hull S, Pott G, Peelor R, Miller B, et al.
Nutrients . 2023 Oct; 15(20). PMID: 37892512
Men are diagnosed with type 2 diabetes at lower body mass indexes than women; the role of skeletal muscle in this sex difference is poorly understood. Type 2 diabetes impacts...
19.
Franczak E, Maurer A, Drummond V, Kugler B, Wells E, Wenger M, et al.
Geroscience . 2023 Oct; 46(2):2207-2222. PMID: 37880490
Age-associated declines in aerobic capacity promote the development of various metabolic diseases. In rats selectively bred for high/low intrinsic aerobic capacity, greater aerobic capacity reduces susceptibility to metabolic disease while...
20.
Batterson P, McGowan E, Borowik A, Kinter M, Miller B, Newsom S, et al.
Physiol Rep . 2023 Oct; 11(20):e15840. PMID: 37857571
High-fat diet (HFD) and exercise remodel skeletal muscle mitochondria. The electron transfer flavoproteins (ETF) transfer reducing equivalents from β-oxidation into the electron transfer system. Exercise may stimulate the synthesis of...