Benjamin E Gross
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Explore the profile of Benjamin E Gross including associated specialties, affiliations and a list of published articles.
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9
Citations
12569
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Recent Articles
1.
Smyth L, Zhou Q, Nguyen B, Yu C, Lepisto E, Arnedos M, et al.
Cancer Discov
. 2020 Jan;
10(4):526-535.
PMID: 31924700
AKT inhibitors have promising activity in -mutant estrogen receptor (ER)-positive metastatic breast cancer, but the natural history of this rare genomic subtype remains unknown. Utilizing AACR Project GENIE, an international...
2.
Wang Q, Armenia J, Zhang C, Penson A, Reznik E, Zhang L, et al.
Sci Data
. 2018 Apr;
5:180061.
PMID: 29664468
Driven by the recent advances of next generation sequencing (NGS) technologies and an urgent need to decode complex human diseases, a multitude of large-scale studies were conducted recently that have...
3.
Janjigian Y, Sanchez-Vega F, Jonsson P, Chatila W, Hechtman J, Ku G, et al.
Cancer Discov
. 2017 Nov;
8(1):49-58.
PMID: 29122777
The incidence of esophagogastric cancer is rapidly rising, but only a minority of patients derive durable benefit from current therapies. Chemotherapy as well as anti-HER2 and PD-1 antibodies are standard...
4.
Zehir A, Benayed R, Shah R, Syed A, Middha S, Kim H, et al.
Nat Med
. 2017 Aug;
23(8):1004.
PMID: 28777785
No abstract available.
5.
Zehir A, Benayed R, Shah R, Syed A, Middha S, Kim H, et al.
Nat Med
. 2017 May;
23(6):703-713.
PMID: 28481359
Tumor molecular profiling is a fundamental component of precision oncology, enabling the identification of genomic alterations in genes and pathways that can be targeted therapeutically. The existence of recurrent targetable...
6.
Ho A, Kannan K, Roy D, Morris L, Ganly I, Katabi N, et al.
Nat Genet
. 2013 May;
45(7):791-8.
PMID: 23685749
Adenoid cystic carcinomas (ACCs) are among the most enigmatic of human malignancies. These aggressive salivary gland cancers frequently recur and metastasize despite definitive treatment, with no known effective chemotherapy regimen....
7.
Cerami E, Gao J, Dogrusoz U, Gross B, Sumer S, Aksoy B, et al.
Cancer Discov
. 2012 May;
2(5):401-4.
PMID: 22588877
The cBio Cancer Genomics Portal (http://cbioportal.org) is an open-access resource for interactive exploration of multidimensional cancer genomics data sets, currently providing access to data from more than 5,000 tumor samples...
8.
Cerami E, Gross B, Demir E, Rodchenkov I, Babur O, Anwar N, et al.
Nucleic Acids Res
. 2010 Nov;
39(Database issue):D685-90.
PMID: 21071392
Pathway Commons (http://www.pathwaycommons.org) is a collection of publicly available pathway data from multiple organisms. Pathway Commons provides a web-based interface that enables biologists to browse and search a comprehensive collection...
9.
Cerami E, Bader G, Gross B, Sander C
BMC Bioinformatics
. 2006 Nov;
7:497.
PMID: 17101041
Background: Biological pathways, including metabolic pathways, protein interaction networks, signal transduction pathways, and gene regulatory networks, are currently represented in over 220 diverse databases. These data are crucial for the...