Beate Eckes
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Explore the profile of Beate Eckes including associated specialties, affiliations and a list of published articles.
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75
Citations
1900
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Recent Articles
11.
Etich J, Rehberg M, Eckes B, Sengle G, Semler O, Zaucke F
Cell Signal
. 2020 Sep;
76:109789.
PMID: 32980496
Osteogenesis imperfecta (OI) is a clinically and genetically heterogeneous connective tissue disorder characterized by bone fragility and skeletal deformity. To maintain skeletal strength and integrity, bone undergoes constant remodeling of...
12.
Schonborn K, Willenborg S, Schulz J, Imhof T, Eming S, Quondamatteo F, et al.
Matrix Biol
. 2020 Sep;
94:57-76.
PMID: 32890632
Skin integrity and function depends to a large extent on the composition of the extracellular matrix, which regulates tissue organization. Collagen XII is a homotrimer with short collagenous domains that...
13.
Kronenberg D, Michel P, Hochstrat E, Wei M, Brinckmann J, Muller M, et al.
Int J Mol Sci
. 2020 Apr;
21(8).
PMID: 32325713
Integrins are a family of transmembrane proteins, involved in substrate recognition and cell adhesion in cross-talk with the extra cellular matrix. In this study, we investigated the influence of integrin...
14.
Ustun Y, Reibetanz M, Brachvogel B, Nischt R, Eckes B, Zigrino P, et al.
Matrix Biol
. 2018 Oct;
80:59-71.
PMID: 30273664
Laminins are the major basement membrane (BM) components and are heterotrimers composed of an α, a β and a γ chain. In skin, laminins are present in basement membranes surrounding...
15.
Do N, Willenborg S, Eckes B, Jungst C, Sengle G, Zaucke F, et al.
J Immunol
. 2018 Jun;
201(2):663-674.
PMID: 29898959
Myeloid cells can be beneficial as well as harmful in tissue regenerative responses. The molecular mechanisms by which myeloid cells control this critical decision of the immune system are not...
16.
Schulz J, Plomann M, Sengle G, Gullberg D, Krieg T, Eckes B
Matrix Biol
. 2018 Feb;
68-69:522-532.
PMID: 29408278
Many different diseases are associated with fibrosis of the skin. The clinical symptoms can vary considerably with a broad range from isolated small areas to the involvement of the entire...
17.
Nuchel J, Ghatak S, Zuk A, Illerhaus A, Morgelin M, Schonborn K, et al.
Autophagy
. 2018 Jan;
14(3):465-486.
PMID: 29297744
TGFB1 (transforming growth factor beta 1) is a potent cytokine playing a driving role in development, fibrosis and cancer. It is synthesized as prodomain-growth factor complex that requires tethering to...
18.
Eckes B, Wang F, Moinzadeh P, Hunzelmann N, Krieg T
Front Med (Lausanne)
. 2017 Sep;
4:120.
PMID: 28868289
Sclerosing skin diseases represent a large number of distinct disease entities, which include systemic sclerosis, localized scleroderma, and scleredema adultorum. These pathologies have a common clinical appearance and share histological...
19.
Eckes B, Wang F, Rittie L, Scherr G, Zigrino P
Methods Mol Biol
. 2017 Aug;
1627:223-233.
PMID: 28836205
Investigation of cell function is often hampered by the complexity of the tissue context. This problem is circumvented by isolating cells from tissues and analyzing their behavior in culture. Most...
20.
Schiller H, Mayr C, Leuschner G, Strunz M, Staab-Weijnitz C, Preisendorfer S, et al.
Am J Respir Crit Care Med
. 2017 Jun;
196(10):1298-1310.
PMID: 28654764
Rationale: Analyzing the molecular heterogeneity of different forms of organ fibrosis may reveal common and specific factors and thus identify potential future therapeutic targets. Objectives: We sought to use proteome-wide...