Beata Vertessy
Overview
Explore the profile of Beata Vertessy including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
10
Citations
72
Followers
0
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Recent Articles
1.
Orgovan Z, Peczka N, Petri L, Abranyi-Balogh P, Randelovic I, Toth S, et al.
Eur J Med Chem
. 2023 Feb;
250:115212.
PMID: 36842271
G12C mutant KRas is considered druggable by allele-specific covalent inhibitors due to the nucleophilic character of the oncogenic mutant cysteine at position 12. Discovery of these inhibitors requires the optimization...
2.
Eszter Szabo J, Nyiri K, Andrasi D, Matejka J, Ozohanics O, Vertessy B
Sci Rep
. 2021 Oct;
11(1):21666.
PMID: 34716399
No abstract available.
3.
Eszter Szabo J, Nyiri K, Andrasi D, Matejka J, Ozohanics O, Vertessy B
Sci Rep
. 2021 Sep;
11(1):19197.
PMID: 34584184
Recently it was proposed that the redox status of cysteines acts as a redox switch to regulate both the oligomeric status and the activity of human dUTPase. In a separate...
4.
Tsagakis I, Vertessy B, Wright D
FEBS Open Bio
. 2021 Feb;
11(2):338-339.
PMID: 33611861
No abstract available.
5.
Ecsedi P, Kiss B, Gogl G, Radnai L, Buday L, Koprivanacz K, et al.
Structure
. 2017 Jul;
25(8):1195-1207.e5.
PMID: 28669632
Annexin A2 (ANXA2) has a versatile role in membrane-associated functions including membrane aggregation, endo- and exocytosis, and it is regulated by post-translational modifications and protein-protein interactions through the unstructured N-terminal...
6.
Kenesi E, Carbonell A, Lozsa R, Vertessy B, Lakatos L
Nucleic Acids Res
. 2017 May;
45(13):7736-7750.
PMID: 28499009
In most eukaryotes, RNA silencing is an adaptive immune system regulating key biological processes including antiviral defense. To evade this response, viruses of plants, worms and insects have evolved viral...
7.
Horvati K, Bacsa B, Szabo N, Fodor K, Balka G, Rusvai M, et al.
Tuberculosis (Edinb)
. 2015 Mar;
95 Suppl 1:S207-11.
PMID: 25728610
New pyridopyrimidine derivatives were defined using a novel HTS in silico docking method (FRIGATE). The target protein was a dUTPase enzyme (EC 3.6.1.23; Rv2697) which plays a key role in...
8.
Horvati K, Bacsa B, Szabo N, David S, Mezo G, Grolmusz V, et al.
Bioconjug Chem
. 2012 Apr;
23(5):900-7.
PMID: 22515329
Mycobacterium tuberculosis is a successful pathogen, and it can survive in infected macrophages in dormant phase for years and decades. The therapy of tuberculosis takes at least six months, and...
9.
Scheich C, Szabadka Z, Vertessy B, Putter V, Grolmusz V, Schade M
PLoS One
. 2011 Dec;
6(12):e28428.
PMID: 22164290
With 1.6 million casualties annually and 2 billion people being infected, tuberculosis is still one of the most pressing healthcare challenges. Here we report on the new computational docking algorithm...
10.
Poppe L, Paizs C, Kovacs K, Irimie F, Vertessy B
Methods Mol Biol
. 2011 Sep;
794:3-19.
PMID: 21956553
Ammonia-lyases catalyze a wide range of processes leading to α,β-unsaturated compounds by elimination of ammonia. In this chapter, ammonia-lyases are reviewed with major emphasis on their synthetic applications in stereoselective...