6.
Tchigvintsev A, Singer A, Flick R, Petit P, Brown G, Evdokimova E
. Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme. Biochem J. 2011; 437(2):243-53.
PMC: 4671291.
DOI: 10.1042/BJ20110304.
View
7.
Nemeth-Pongracz V, Barabas O, Fuxreiter M, Simon I, Pichova I, Rumlova M
. Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins. Nucleic Acids Res. 2006; 35(2):495-505.
PMC: 1802613.
DOI: 10.1093/nar/gkl1074.
View
8.
Kan L, Jain S, Cook W, Cao W, Usuda N, Yeldandi A
. Cloning and expression of the mouse deoxyuridine triphosphate nucleotidohydrolase gene: differs from the rat enzyme in that it lacks nuclear receptor interacting LXXLL motif. Gene Expr. 2000; 8(4):231-46.
PMC: 6157361.
View
9.
Vertessy B, Toth J
. Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases. Acc Chem Res. 2008; 42(1):97-106.
PMC: 2732909.
DOI: 10.1021/ar800114w.
View
10.
Ladner R, Lynch F, Groshen S, Xiong Y, Sherrod A, Caradonna S
. dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer. Cancer Res. 2000; 60(13):3493-503.
View
11.
Whittingham J, Leal I, Nguyen C, Kasinathan G, Bell E, Jones A
. dUTPase as a platform for antimalarial drug design: structural basis for the selectivity of a class of nucleoside inhibitors. Structure. 2005; 13(2):329-38.
DOI: 10.1016/j.str.2004.11.015.
View
12.
Boesch P, Weber-Lotfi F, Ibrahim N, Tarasenko V, Cosset A, Paulus F
. DNA repair in organelles: Pathways, organization, regulation, relevance in disease and aging. Biochim Biophys Acta. 2010; 1813(1):186-200.
DOI: 10.1016/j.bbamcr.2010.10.002.
View
13.
Donnelly D, Rawlins C, DeHart C, Fornelli L, Schachner L, Lin Z
. Best practices and benchmarks for intact protein analysis for top-down mass spectrometry. Nat Methods. 2019; 16(7):587-594.
PMC: 6719561.
DOI: 10.1038/s41592-019-0457-0.
View
14.
Go Y, Jones D
. Redox compartmentalization in eukaryotic cells. Biochim Biophys Acta. 2008; 1780(11):1273-90.
PMC: 2601570.
DOI: 10.1016/j.bbagen.2008.01.011.
View
15.
Merenyi G, Kovari J, Toth J, Takacs E, Zagyva I, Erdei A
. Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism. Nucleosides Nucleotides Nucleic Acids. 2011; 30(6):369-90.
DOI: 10.1080/15257770.2011.582849.
View
16.
Pecsi I, Leveles I, Harmat V, Vertessy B, Toth J
. Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase. Nucleic Acids Res. 2010; 38(20):7179-86.
PMC: 2978360.
DOI: 10.1093/nar/gkq584.
View
17.
Takacs E, Barabas O, Petoukhov M, Svergun D, Vertessy B
. Molecular shape and prominent role of beta-strand swapping in organization of dUTPase oligomers. FEBS Lett. 2009; 583(5):865-71.
DOI: 10.1016/j.febslet.2009.02.011.
View
18.
Dos Santos R, Daures M, Philippi A, Romero S, Marselli L, Marchetti P
. dUTPase () Is Mutated in a Novel Monogenic Syndrome With Diabetes and Bone Marrow Failure. Diabetes. 2017; 66(4):1086-1096.
DOI: 10.2337/db16-0839.
View
19.
Kerepesi C, Szabo J, Papp-Kadar V, Dobay O, Szabo D, Grolmusz V
. Life without dUTPase. Front Microbiol. 2016; 7:1768.
PMC: 5122711.
DOI: 10.3389/fmicb.2016.01768.
View
20.
Kovari J, Barabas O, Takacs E, Bekesi A, Dubrovay Z, Pongracz V
. Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme. J Biol Chem. 2004; 279(17):17932-44.
DOI: 10.1074/jbc.M313643200.
View