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Bastien Mangeat

Explore the profile of Bastien Mangeat including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 2321
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Recent Articles
1.
Uysal Ozdemir O, Krapp A, Mangeat B, Spaltenstein M, Simanis V
J Cell Sci . 2024 Jan; 137(1). PMID: 38197775
The septation initiation network (SIN) is a conserved signal transduction network, which is important for cytokinesis in Schizosaccharomyces pombe. The SIN component Etd1p is required for association of some SIN...
2.
Gulen M, Samson N, Keller A, Schwabenland M, Liu C, Gluck S, et al.
Nature . 2023 Aug; 620(7973):374-380. PMID: 37532932
Low-grade inflammation is a hallmark of old age and a central driver of ageing-associated impairment and disease. Multiple factors can contribute to ageing-associated inflammation; however, the molecular pathways that transduce...
3.
Vkovski P, Gultom M, Kelly J, Steiner S, Russeil J, Mangeat B, et al.
PLoS Biol . 2021 Mar; 19(3):e3001158. PMID: 33780434
Since its emergence in December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread globally and become a major public health burden. Despite its close phylogenetic relationship to SARS-CoV,...
4.
Alpern D, Gardeux V, Russeil J, Mangeat B, Meireles-Filho A, Breysse R, et al.
Genome Biol . 2019 Apr; 20(1):71. PMID: 30999927
Despite its widespread use, RNA-seq is still too laborious and expensive to replace RT-qPCR as the default gene expression analysis method. We present a novel approach, BRB-seq, which uses early...
5.
Penaloza MacMaster P, Shields J, Alayo Q, Cabral C, Jimenez J, Mondesir J, et al.
Vaccine . 2016 Dec; 35(1):1-9. PMID: 27899229
An important focus in vaccine research is the design of vaccine vectors with low seroprevalence and high immunogenicity. Replication-incompetent lymphocytic choriomeningitis virus (rLCMV) vectors do not elicit vector-neutralizing antibody responses,...
6.
Schleiss M, Berka U, Watson E, Aistleithner M, Kiefmann B, Mangeat B, et al.
Clin Vaccine Immunol . 2016 Nov; 24(1). PMID: 27795301
Subunit vaccines for prevention of congenital cytomegalovirus (CMV) infection based on glycoprotein B (gB) and pp65 are in clinical trials, but it is unclear whether simultaneous vaccination with both antigens...
7.
Friedli M, Turelli P, Kapopoulou A, Rauwel B, Castro-Diaz N, Rowe H, et al.
Genome Res . 2014 Jun; 24(8):1251-9. PMID: 24879558
Endogenous retroelements (EREs) account for about half of the mouse or human genome, and their potential as insertional mutagens and transcriptional perturbators is suppressed by early embryonic epigenetic silencing. Here,...
8.
Kaur I, Puri M, Ahmed Z, Blanchet F, Mangeat B, Piguet V
PLoS One . 2013 Sep; 8(9):e73780. PMID: 24040067
Ribosome-inactivating proteins (RIPs) are endowed with several medicinal properties, including antiviral activity. We demonstrate here that the recently identified type I RIP from Momordica balsamina also possesses antiviral activity, as...
9.
Blanchet F, Stalder R, Czubala M, Lehmann M, Rio L, Mangeat B, et al.
Retrovirology . 2013 Jan; 10:6. PMID: 23311681
Background: Dendritic cells and their subsets, located at mucosal surfaces, are among the first immune cells to encounter disseminating pathogens. The cellular restriction factor BST-2/tetherin (also known as CD317 or...
10.
Mangeat B, Cavagliotti L, Lehmann M, Gers-Huber G, Kaur I, Thomas Y, et al.
J Biol Chem . 2012 Apr; 287(26):22015-29. PMID: 22493439
Influenza virus infections lead to a burst of type I interferon (IFN) in the human respiratory tract, which most probably accounts for a rapid control of the virus. Although in...