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Barry Jones

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Recent Articles
1.
Bivi N, Graham D, Joglekar L, McGuire K, Stoop J, Zoghbi J, et al.
Bioanalysis . 2025 Jan; 17(4):211-248. PMID: 39862107
The 18th Workshop on Recent Issues in Bioanalysis (18th WRIB) took place in San Antonio, TX, USA on May 6-10, 2024. Over 1100 professionals representing pharma/biotech companies, CROs, and multiple...
2.
Baratta M, Jian W, Hengel S, Kaur S, Cunliffe J, Boer J, et al.
Bioanalysis . 2024 Jun; 16(9):307-364. PMID: 38913185
The 17 Workshop on Recent Issues in Bioanalysis (17 WRIB) took place in Orlando, FL, USA on June 19-23, 2023. Over 1000 professionals representing pharma/biotech companies, CROs, and multiple regulatory...
3.
Poplawski S, Hallett R, Dornan M, Novakowski K, Pan S, Belanger A, et al.
J Nucl Med . 2023 Dec; 65(1):100-108. PMID: 38050111
The overexpression of fibroblast activation protein-α (FAP) in solid cancers relative to levels in normal tissues has led to its recognition as a target for delivering agents directly to tumors....
4.
Gardner I, Xu M, Han C, Wang Y, Jiao X, Jamei M, et al.
Xenobiotica . 2022 Oct; 52(8):943-956. PMID: 36222269
Non-specific binding in metabolism systems leads to an underestimation of the true intrinsic metabolic clearance of compounds being studied. Therefore binding needs to be accounted for when extrapolating data to...
5.
Taylor S, Henshall J, Beaumont K, Hood S, Jones B, Wilson I, et al.
Xenobiotica . 2022 Oct; 52(8):767-769. PMID: 36214565
No abstract available.
6.
Dai W, Arciero V, Craig E, Fraser B, Arias J, Boehm D, et al.
Curr Oncol . 2021 Oct; 28(5):4174-4183. PMID: 34677272
The Canadian Real-world Evidence for Value in Cancer Drugs (CanREValue) Collaboration was established to develop a framework for generating and using real-world evidence (RWE) to inform the reassessment of cancer...
7.
Pike A, Jones B, Markandu R, ONeill D
Drug Metab Dispos . 2021 Jun; 49(9):736-742. PMID: 34135088
Inconsistencies in pharmacokinetic parameters between individual animals in preclinical studies are a common occurrence. Often such differences between animals are simply accepted as experimental variability rather than as indications of...
8.
Wong S, Ramsden D, Dallas S, Fung C, Einolf H, Palamanda J, et al.
Drug Metab Dispos . 2020 Nov; 49(1):94-110. PMID: 33139460
Translational and ADME Sciences Leadership Group Induction Working Group (IWG) presents an analysis on the time course for cytochrome P450 induction in primary human hepatocytes. Induction of CYP1A2, CYP2B6, and...
9.
De Sousa Mendes M, Orton A, Humphries H, Jones B, Gardner I, Neuhoff S, et al.
Drug Metab Dispos . 2020 Sep; 48(11):1231-1238. PMID: 32893186
Aldehyde oxidase (AO) efficiently metabolizes a range of compounds with N-containing heterocyclic aromatic rings and/or aldehydes. The limited knowledge of AO activity and abundance (in vitro and in vivo) has...
10.
Kellie J, Tran J, Jian W, Jones B, Mehl J, Ge Y, et al.
J Am Soc Mass Spectrom . 2020 Sep; 32(8):1886-1900. PMID: 32869982
Recent advancements in immunocapture methods and mass spectrometer technology have enabled intact protein mass spectrometry to be applied for the characterization of antibodies and other large biotherapeutics from in-life studies....