Barbie K Ganser-Pornillos
Overview
Explore the profile of Barbie K Ganser-Pornillos including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
41
Citations
2844
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Buckmaster M, Zadrozny K, Ganser-Pornillos B, Pornillos O, Goff S
J Virol
. 2021 Jul;
95(19):e0061521.
PMID: 34287037
The transition from an immature to a fully infectious mature retrovirus particle is associated with molecular switches that trigger dramatic conformational changes in the structure of the Gag proteins. A...
12.
Christensen D, Ganser-Pornillos B, Johnson J, Pornillos O, Sundquist W
Science
. 2020 Oct;
370(6513).
PMID: 33033190
During the first half of the viral life cycle, HIV-1 reverse transcribes its RNA genome and integrates the double-stranded DNA copy into a host cell chromosome. Despite progress in characterizing...
13.
Ward A, Kiessling V, Pornillos O, White J, Ganser-Pornillos B, Tamm L
J Biol Chem
. 2020 Aug;
295(45):15183-15195.
PMID: 32788212
To enter a cell and establish infection, HIV must first fuse its lipid envelope with the host cell plasma membrane. Whereas the process of HIV membrane fusion can be tracked...
14.
Yu A, Skorupka K, Pak A, Ganser-Pornillos B, Pornillos O, Voth G
Nat Commun
. 2020 Mar;
11(1):1307.
PMID: 32161265
The tripartite-motif protein, TRIM5α, is an innate immune sensor that potently restricts retrovirus infection by binding to human immunodeficiency virus capsids. Higher-ordered oligomerization of this protein forms hexagonally patterned structures...
15.
Skorupka K, Roganowicz M, Christensen D, Wan Y, Pornillos O, Ganser-Pornillos B
Sci Adv
. 2019 Dec;
5(11):eaaw3631.
PMID: 31807695
TRIM5α is a restriction factor that senses incoming retrovirus cores through an unprecedented mechanism of nonself recognition. TRIM5α assembles a hexagonal lattice that avidly binds the capsid shell, which surrounds...
16.
Kucharska I, Ding P, Zadrozny K, Dick R, Summers M, Ganser-Pornillos B, et al.
J Virol
. 2019 Dec;
94(5).
PMID: 31801870
The assembly of an orthoretrovirus such as HIV-1 requires the coordinated functioning of multiple biochemical activities of the viral Gag protein. These activities include membrane targeting, lattice formation, packaging of...
17.
Ganser-Pornillos B, Pornillos O
Nat Rev Microbiol
. 2019 Jul;
17(9):546-556.
PMID: 31312031
Mammalian cells express a variety of innate immune proteins - known as restriction factors - which defend against invading retroviruses such as HIV-1. Two members of the tripartite motif protein...
18.
Pornillos O, Ganser-Pornillos B
Curr Opin Virol
. 2019 Jun;
36:47-55.
PMID: 31185449
During retrovirus maturation, cleavage of the precursor structural Gag polyprotein by the viral protease induces architectural rearrangement of the virus particle from an immature into a mature, infectious form. The...
19.
Dick R, Zadrozny K, Xu C, Schur F, Lyddon T, Ricana C, et al.
Nature
. 2018 Aug;
563(7731):E22.
PMID: 30158708
In this Letter, the Protein Data Bank (PDB) accessions were incorrectly listed as '6BH5, 6BHT and 6BHS' instead of '6BHR, 6BHT and 6BHS'; this has been corrected online.
20.
Dick R, Zadrozny K, Xu C, Schur F, Lyddon T, Ricana C, et al.
Nature
. 2018 Aug;
560(7719):509-512.
PMID: 30069050
A short, 14-amino-acid segment called SP1, located in the Gag structural protein, has a critical role during the formation of the HIV-1 virus particle. During virus assembly, the SP1 peptide...