Barbel Rohrer
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Explore the profile of Barbel Rohrer including associated specialties, affiliations and a list of published articles.
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93
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7916
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Recent Articles
31.
Parsons N, Annamalai B, Obert E, Schnabolk G, Tomlinson S, Rohrer B
Mol Immunol
. 2019 Feb;
108:8-12.
PMID: 30763805
Age-related macular degeneration (AMD) is the leading cause of blindness in the US. Polymorphisms in complement components are associated with increased AMD risk, and it has been hypothesized that an...
32.
Ishii M, Rohrer B
Cell Death Dis
. 2018 Jul;
9(8):786.
PMID: 30013064
The PDF and HTML versions of the article have been updated to include the Creative Commons Attribution 4.0 International License information.
33.
Rohrer B
Adv Exp Med Biol
. 2018 May;
1074:45-51.
PMID: 29721926
Age-related macular degeneration (AMD) is the leading cause of blindness in the USA. Polymorphisms in various complement components are associated with an increased risk for AMD, and it has been...
34.
Shah N, Ishii M, Brandon C, Ablonczy Z, Cai J, Liu Y, et al.
Biochim Biophys Acta Mol Basis Dis
. 2018 Apr;
1864(8):2610-2622.
PMID: 29684588
Retinal pigment epithelium (RPE) alterations in age-related macular degeneration occur in patches, potentially involving long-distance communication between damaged and healthy areas. Communication along the epithelium might be mediated by extracellular...
35.
Annamalai B, Parsons N, Belhaj M, Brandon C, Potts J, Rohrer B
Transl Vis Sci Technol
. 2018 Mar;
7(2):3.
PMID: 29576927
Purpose: Age-related macular degeneration (AMD) is a slowly progressing disease, and risk appears to be tied to an overactive complement system. We have previously demonstrated that mouse choroidal neovascularization (CNV)...
36.
Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, et al.
Mol Ther Methods Clin Dev
. 2017 Dec;
9:1-11.
PMID: 29234687
Complement activation plays a significant role in age-related macular degeneration (AMD) pathogenesis, and polymorphisms interfering with factor H (fH) function, a complement alternative pathway (AP) inhibitor, are associated with increased...
37.
Shi Y, Obert E, Rahman B, Rohrer B, Lobo G
Sci Rep
. 2017 Nov;
7(1):16207.
PMID: 29176573
Vitamin A (all-trans retinol) plays critical roles in mammalian development and vision. Since vitamin A is food-derived, tissue-specific uptake and storage mechanism are needed. In the eye, uptake of RBP4-retinol...
38.
39.
Lobo G, Fulmer D, Guo L, Zuo X, Dang Y, Kim S, et al.
J Biol Chem
. 2017 Jul;
292(36):14814-14826.
PMID: 28729419
We previously have shown that the highly conserved eight-protein exocyst trafficking complex is required for ciliogenesis in kidney tubule cells. We hypothesized here that ciliogenic programs are conserved across organs...
40.
Busch C, Annamalai B, Abdusalamova K, Reichhart N, Huber C, Lin Y, et al.
Front Immunol
. 2017 Jul;
8:703.
PMID: 28663750
Purpose: The retinal pigment epithelium (RPE) is a main target for complement activation in age-related macular degeneration (AMD). The anaphylatoxins C3a and C5a have been thought to mostly play a...