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Barbara Leibiger

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Recent Articles
1.
Lazzeri-Barcelo F, Ciardo P, Leibiger B, Leibiger I, Berggren P, Moruzzi N
J Vis Exp . 2024 Apr; (205). PMID: 38619277
Biomedical studies of the liver in mammals are hindered by the lack of methods for in vivo noninvasive longitudinal imaging at cellular resolution. Until now, optical imaging of the liver...
2.
Branstrom R, van Krieken P, Frobom R, Juhlin C, Shabo I, Leibiger B, et al.
Cell Transplant . 2024 Mar; 33:9636897241241995. PMID: 38554052
The parathyroid cell is a vital regulator of extracellular calcium levels, operating through the secretion of parathyroid hormone (PTH). Despite its importance, the regulation of PTH secretion remains complex and...
3.
Lazzeri-Barcelo F, Oliva-Vilarnau N, Baniol M, Leibiger B, Bergmann O, Lauschke V, et al.
Nat Commun . 2024 Jan; 15(1):767. PMID: 38278787
Longitudinal monitoring of liver function in vivo is hindered by the lack of high-resolution non-invasive imaging techniques. Using the anterior chamber of the mouse eye as a transplantation site, we...
4.
Yu J, Leibiger B, Yang S, Shears S, Leibiger I, Berggren P, et al.
Biomolecules . 2023 Jun; 13(6). PMID: 37371464
Multiple inositol polyphosphate phosphatase (MINPP1) is an enigmatic enzyme that is responsible for the metabolism of inositol hexakisphosphate (Ins) and inositol 1,3,4,5,6 pentakisphosphate (Ins(1,3,4,5,6) in mammalian cells, despite being restricted...
5.
Moruzzi N, Leibiger B, Barker C, Leibiger I, Berggren P
Adv Biol Regul . 2022 Oct; 87:100919. PMID: 36266190
Pancreatic islets are micro-organs composed of a mixture of endocrine and non-endocrine cells, where the former secrete hormones and peptides necessary for metabolic homeostasis. Through vasculature and innervation the cells...
6.
Moruzzi N, Valladolid-Acebes I, Kannabiran S, Bulgaro S, Burtscher I, Leibiger B, et al.
Life Sci Alliance . 2022 Sep; 5(12). PMID: 36104081
Primary cilia have recently emerged as cellular signaling organelles. Their homeostasis and function require a high amount of energy. However, how energy depletion and mitochondria impairment affect cilia have barely...
7.
Branstrom R, Berglund E, Frobom R, Leibiger I, Leibiger B, Aspinwall C, et al.
Biochem Biophys Rep . 2022 Apr; 30:101260. PMID: 35434386
Background: The ATP-sensitive K (K(ATP)) channel is found in a variety of tissues extending from the heart and vascular smooth muscles to the endocrine pancreas and brain. Common to all...
8.
Heitz B, Branstrom R, Yang W, Huang Y, Moede T, Leibiger I, et al.
Sci Rep . 2021 Nov; 11(1):21539. PMID: 34728728
ATP-sensitive K (K) channels couple cellular metabolism to electrical activity in many cell types. Wild-type K channels are comprised of four pore forming (Kir6.x) and four regulatory (sulfonylurea receptor, SURx)...
9.
Leibiger B, Moede T, Valladolid-Acebes I, Paschen M, Visa M, Leibiger I, et al.
Metabolites . 2021 Jul; 11(6). PMID: 34198579
The pancreatic islets of Langerhans consist of endocrine cells that secrete peptide hormones into the blood circulation in response to metabolic stimuli. When transplanted into the anterior chamber of the...
10.
Moruzzi N, Lazzeri-Barcelo F, Valladolid-Acebes I, Moede T, Paschen M, Leibiger B, et al.
J Cell Mol Med . 2021 Mar; 25(10):4800-4813. PMID: 33742502
The two insulin receptor (IR) isoforms IR-A and IR-B are responsible for the pleiotropic actions of insulin and insulin-like growth factors. Consequently, changes in IR isoform expression and in the...