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Barbara Brouwers

Explore the profile of Barbara Brouwers including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Wu Q, Brouwers B, Dalmasso B, Kenis C, Vuylsteke P, Debrock G, et al.
Transl Oncol . 2022 Sep; 25:101527. PMID: 36067542
Background: The exact impact of chemotherapy on the immune system of older patients with breast cancer is not well known. A longitudinal study was performed investigating the evolution of the...
2.
Wildiers H, Meyskens T, Marreaud S, Dal Lago L, Vuylsteke P, Curigliano G, et al.
Breast . 2022 May; 64:100-111. PMID: 35636341
Introduction: Older patients are at higher risk of chemotherapy-induced toxicity, raising interest in less toxic anti-HER2 regimens for older persons with HER2-positive (HER2+) metastatic breast cancer (MBC). Patients And Methods:...
3.
Dal Lago L, Uwimana A, Coens C, Vuylsteke P, Curigliano G, Brouwers B, et al.
J Geriatr Oncol . 2022 Feb; 13(5):582-593. PMID: 35101364
Introduction: European Organisation for Research and Treatment of Cancer (EORTC) phase II trial (75111-10114) demonstrated that combining pertuzumab with trastuzumab plus cyclophosphamide (TPM) improved median progression-free survival by seven months...
4.
Quinten C, Kenis C, Hamaker M, Coolbrandt A, Brouwers B, Dal Lago L, et al.
Eur J Cancer Care (Engl) . 2020 Jun; 29(5):e13278. PMID: 32557904
Objective: The objective of this study was to assess the relationship between geriatric assessment (GA) and health-related Quality-of-Life (HRQOL) in older patients with breast cancer. Methods: Patients were assigned either...
5.
Mayrhofer M, De Laere B, Whitington T, Van Oyen P, Ghysel C, Ampe J, et al.
Genome Med . 2018 Nov; 10(1):85. PMID: 30458854
Background: There are multiple existing and emerging therapeutic avenues for metastatic prostate cancer, with a common denominator, which is the need for predictive biomarkers. Circulating tumor DNA (ctDNA) has the...
6.
Dalmasso B, Hatse S, Brouwers B, Laenen A, Berben L, Kenis C, et al.
BMC Cancer . 2018 Oct; 18(1):1014. PMID: 30348127
Background: MicroRNAs (miRNAs) are important regulators of cellular function and have been associated with both aging and cancer, but the impact of chemotherapy on age-related miRNAs has barely been studied....
7.
De Laere B, Oeyen S, Mayrhofer M, Whitington T, Van Dam P, Van Oyen P, et al.
Clin Cancer Res . 2018 Sep; 25(6):1766-1773. PMID: 30209161
Purpose: To infer the prognostic value of simultaneous androgen receptor () and profiling in liquid biopsies from patients with metastatic castration-resistant prostate cancer (mCRPC) starting a new line of signaling...
8.
Speigl L, Grieb A, Janssen N, Hatse S, Brouwers B, Smeets A, et al.
J Geriatr Oncol . 2018 Apr; 9(6):606-612. PMID: 29685380
Objectives: The global health status of older patients with cancer influences their clinical course, but little is known regarding the influence of the immune system on the global health of...
9.
Wildiers H, Tryfonidis K, Dal Lago L, Vuylsteke P, Curigliano G, Waters S, et al.
Lancet Oncol . 2018 Feb; 19(3):323-336. PMID: 29433963
Background: Despite the high incidence of metastatic breast cancer and its related mortality in the elderly population, our knowledge about optimal treatment for older patients with cancer is far from...
10.
De Laere B, Oeyen S, Van Oyen P, Ghysel C, Ampe J, Ost P, et al.
Prostate . 2018 Feb; 78(6):435-445. PMID: 29431193
Background: The outcome to treatment administered to patients with metastatic castration-resistant prostate cancer (mCRPC) greatly differs between individuals, underlining the need for biomarkers guiding treatment decision making. Objective: To investigate...