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Balakuntalam S Kasinath

Explore the profile of Balakuntalam S Kasinath including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 2366
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Recent Articles
1.
Lee H, Sun Y, Das F, Ju W, Nair V, Kevil C, et al.
JCI Insight . 2025 Jan; 10(1. PMID: 39782685
The role played by anionic channels in diabetic kidney disease (DKD) is not known. Chloride channel accessory 1 (CLCA1) facilitates the activity of TMEM16A (Anoctamin-1), a Ca2+-dependent Cl- channel. We...
2.
Das F, Ghosh-Choudhury N, Kasinath B, Sharma K, Ghosh Choudhury G
PLoS One . 2025 Jan; 20(1):e0311828. PMID: 39761275
High glucose milieu in diabetes induces proximal tubular epithelial cells in the kidney to undergo hypertrophy and matrix protein expansion via Akt/mTORC1 signaling, leading to renal fibrosis. The familial Parkinson's...
3.
Das F, Ghosh-Choudhury N, Kasinath B, Sharma K, Ghosh Choudhury G
Exp Cell Res . 2024 Jun; 440(1):114116. PMID: 38830568
During the progression of diabetic kidney disease, proximal tubular epithelial cells respond to high glucose to induce hypertrophy and matrix expansion leading to renal fibrosis. Recently, a non-canonical PTEN has...
4.
Lee H, Min L, Gao J, Matta S, Drel V, Saliba A, et al.
Diabetes . 2024 Apr; 73(7):1167-1177. PMID: 38656940
Article Highlights:
5.
Debnath S, Thomas N, Saliba A, Kottewar S, Grant S, Kasinath B, et al.
J Nephrol . 2023 Apr; 36(4):1083-1085. PMID: 37036660
No abstract available.
6.
Das F, Ghosh-Choudhury N, Maity S, Kasinath B, Ghosh Choudhury G
FEBS Lett . 2023 Feb; 597(9):1300-1316. PMID: 36775967
The plasticity of proximal tubular epithelial cells in response to TGFβ contributes to the expression of TWIST1 to drive renal fibrosis. The mechanism of TWIST1 expression is not known. We...
7.
Das F, Ghosh-Choudhury N, Maity S, Kasinath B, Ghosh Choudhury G
J Biol Chem . 2022 Jul; 298(9):102246. PMID: 35835217
Proximal tubular epithelial cells respond to transforming growth factor β (TGFβ) to synthesize collagen I (α2) during renal fibrosis. The oncoprotein DJ-1 has previously been shown to promote tumorigenesis and...
8.
Lee H, Gonzalez O, Dick E, Donati A, Feliers D, Ghosh Choudhury G, et al.
J Gerontol A Biol Sci Med Sci . 2021 Sep; 77(1):84. PMID: 34542600
No abstract available.
9.
Kasinath B, Lee H
Adv Exp Med Biol . 2021 Jul; 1315:17-50. PMID: 34302687
Hydrogen sulfide (HS) is constitutively synthesized in the kidney. Recent investigations suggest a role for HS in the regulation of fundamental kidney physiological events including arterial blood flow, glomerular filtration,...
10.
Das F, Bera A, Ghosh-Choudhury N, Sataranatarajan K, Kamat A, Kasinath B, et al.
Cell Signal . 2021 Jul; 86:110072. PMID: 34224844
Function of mTORC1 and mTORC2 has emerged as a driver of mesangial cell pathologies in diabetic nephropathy. The mechanism of mTOR activation is poorly understood in this disease. Deptor is...