Nandini Ghosh-Choudhury
Overview
Explore the profile of Nandini Ghosh-Choudhury including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
56
Citations
1563
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Das F, Ghosh-Choudhury N, Kasinath B, Sharma K, Ghosh Choudhury G
PLoS One
. 2025 Jan;
20(1):e0311828.
PMID: 39761275
High glucose milieu in diabetes induces proximal tubular epithelial cells in the kidney to undergo hypertrophy and matrix protein expansion via Akt/mTORC1 signaling, leading to renal fibrosis. The familial Parkinson's...
2.
Das F, Ghosh-Choudhury N, Kasinath B, Sharma K, Ghosh Choudhury G
Exp Cell Res
. 2024 Jun;
440(1):114116.
PMID: 38830568
During the progression of diabetic kidney disease, proximal tubular epithelial cells respond to high glucose to induce hypertrophy and matrix expansion leading to renal fibrosis. Recently, a non-canonical PTEN has...
3.
Das F, Ghosh-Choudhury N, Maity S, Kasinath B, Ghosh Choudhury G
FEBS Lett
. 2023 Feb;
597(9):1300-1316.
PMID: 36775967
The plasticity of proximal tubular epithelial cells in response to TGFβ contributes to the expression of TWIST1 to drive renal fibrosis. The mechanism of TWIST1 expression is not known. We...
4.
Das F, Ghosh-Choudhury N, Maity S, Kasinath B, Ghosh Choudhury G
J Biol Chem
. 2022 Jul;
298(9):102246.
PMID: 35835217
Proximal tubular epithelial cells respond to transforming growth factor β (TGFβ) to synthesize collagen I (α2) during renal fibrosis. The oncoprotein DJ-1 has previously been shown to promote tumorigenesis and...
5.
Das F, Bera A, Ghosh-Choudhury N, Sataranatarajan K, Kamat A, Kasinath B, et al.
Cell Signal
. 2021 Jul;
86:110072.
PMID: 34224844
Function of mTORC1 and mTORC2 has emerged as a driver of mesangial cell pathologies in diabetic nephropathy. The mechanism of mTOR activation is poorly understood in this disease. Deptor is...
6.
Maity S, Das F, Kasinath B, Ghosh-Choudhury N, Ghosh Choudhury G
J Biol Chem
. 2020 Aug;
295(42):14262-14278.
PMID: 32732288
Interaction of transforming growth factor-β (TGFβ)-induced canonical signaling with the noncanonical kinase cascades regulates glomerular hypertrophy and matrix protein deposition, which are early features of glomerulosclerosis. However, the specific target...
7.
Maity S, Das F, Ghosh-Choudhury N, Kasinath B, Ghosh Choudhury G
FEBS Lett
. 2019 Jun;
593(16):2261-2272.
PMID: 31240704
The mechanism of PTEN repression by high glucose in diabetic nephropathy is not known. Using proximal tubular cells, we show that inhibition of PI3 kinase/Akt and their inactive enzymes prevents...
8.
Das F, Maity S, Ghosh-Choudhury N, Kasinath B, Ghosh Choudhury G
J Biol Chem
. 2019 Apr;
294(24):9440-9460.
PMID: 31028173
S6 kinase acts as a driver for renal hypertrophy and matrix accumulation, two key pathologic signatures of diabetic nephropathy. As a post-translational modification, S6 kinase undergoes acetylation at the C...
9.
Das F, Ghosh-Choudhury N, Lee D, Gorin Y, Kasinath B, Ghosh Choudhury G
PLoS One
. 2018 Nov;
13(11):e0207285.
PMID: 30444896
TGFβ promotes podocyte hypertrophy and expression of matrix proteins in fibrotic kidney diseases such as diabetic nephropathy. Both mTORC1 and mTORC2 are hyperactive in response to TGFβ in various renal...
10.
Maity S, Bera A, Ghosh-Choudhury N, Das F, Kasinath B, Ghosh Choudhury G
Exp Cell Res
. 2018 Feb;
364(1):5-15.
PMID: 29397070
TGFβ contributes to mesangial cell hypertrophy and matrix protein increase in various kidney diseases including diabetic nephropathy. Deptor is an mTOR-interacting protein and suppresses mTORC1 and mTORC2 activities. We have...