B P Roques
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Explore the profile of B P Roques including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Delay-Goyet P, Zajac J, Roques B
Neurochem Int
. 2010 May;
16(3):341-68.
PMID: 20504578
The binding properties of [(3)H]DSTBULET, a new potent and specific ligand for ?-opioid binding sites, were characterized using slices from rat brain striatum. Specific [(3)H]DSTBULET binding reached steady-state within 60...
2.
Pelaprat D, Broer Y, Studler J, Peschanski M, Tassin J, Glowinski J, et al.
Neurochem Int
. 2010 May;
10(4):495-508.
PMID: 20501122
[(3)H]Boc[Nle(28,31)]CCK(27)-(33) ([(3)H]BDNL-CCK(7)) is a new ligand for cholecystokinin (CCK) receptors, endowed with a high specific activity (100 Ci/mmol). Binding sites for this ligand were visualized in the rat brain by...
3.
Goldman S, Pelaprat D, Van Reeth O, Roques B, Vanderhaeghen J
Neurochem Int
. 2010 May;
10(4):467-71.
PMID: 20501119
Carboxyl-terminal cholecystokinin octapeptide (CCK8) binding sites were studied in the human cerebellar system by autoradiography. High affinity CCK8 binding sites were demonstrated in the main cerebellar afferent nuclei, namely the...
4.
Benturquia N, Le Guen S, Canestrelli C, Lagente V, Apiou G, Roques B, et al.
Neuroscience
. 2007 Oct;
149(3):477-86.
PMID: 17905521
Nitrous oxide (N(2)O), a pharmacological active gas and an antagonist of N-methyl-D-aspartic acid receptors, has been reported to be effective in the treatment of alcohol and tobacco withdrawal syndrome. However,...
5.
Siddiqui K, Del Valle L, Morellet N, Cui J, Ghafouri M, Mukerjee R, et al.
Oncogene
. 2007 Jul;
27(1):32-43.
PMID: 17653096
The human immunodeficiency virus type 1 (HIV-1) viral protein R (vpr) gene is an evolutionarily conserved gene among the primate lentiviruses. Several functions are attributed to Vpr including the ability...
6.
Cordonnier L, Sanchez M, Roques B, Noble F
Br J Pharmacol
. 2007 Mar;
151(1):94-102.
PMID: 17351659
Background And Purpose: Maintenance treatments with methadone or buprenorphine are more or less efficient procedures for helping heroin addicts to stop or reduce drug abuse. Another approach to treat opiate...
7.
Sabbah E, Druillennec S, Morellet N, Bouaziz S, Kroemer G, Roques B
Chem Biol Drug Des
. 2006 Feb;
67(2):145-54.
PMID: 16492162
The HIV-1 protein Vpr circulates in the serum of seropositive individuals and in the cerebrospinal fluid of AIDS patients with neurological disorders. Vpr triggers apoptosis of numerous cell types after...
8.
Nieto M, Guen S, Kieffer B, Roques B, Noble F
Neuroscience
. 2005 Aug;
135(2):305-13.
PMID: 16112476
The endogenous pentapeptide enkephalins bind to the mu and delta opioid receptors, with a slightly higher affinity for the latter. It remains a controversy regarding the respective physiological role of...
9.
Cordonnier L, Sanchez M, Roques B, Noble F
Neuroscience
. 2005 Aug;
135(1):1-10.
PMID: 16084652
The endogenous opioid system is known to have a great influence on the dopaminergic system. Conversely, blockade of the dopaminergic system in D2 receptor knock-out mice triggers an increase in...
10.
Ramboarina S, Druillennec S, Morellet N, Bouaziz S, Roques B
J Virol
. 2004 May;
78(12):6682-7.
PMID: 15163759
The modification of zinc-binding residues inside the conserved CCHC motif of human immunodeficiency virus type 1 NCp7, in particular into CCHH, induces a complete loss of infectivity. Since the mutant...