B M Babior
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Explore the profile of B M Babior including associated specialties, affiliations and a list of published articles.
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202
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6134
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Recent Articles
1.
Fox H, Togni P, Babior B
Immunol Today
. 2014 Oct;
6(11):327-8.
PMID: 25291002
No abstract available.
2.
Babior B, Lambeth J, Nauseef W
Arch Biochem Biophys
. 2002 Feb;
397(2):342-4.
PMID: 11795892
The NADPH oxidase of phagocytes catalyzes the conversion of oxygen to O2(-). This multicomponent enzyme complex contains five essential protein components, two in the membrane and three in the cytosol....
3.
Catz S, Johnson J, Babior B
Proc Natl Acad Sci U S A
. 2001 Sep;
98(20):11230-5.
PMID: 11553774
In this work, we demonstrate that the phosphatidylinositol 3,4,5-trisphosphate-binding protein JFC1 is an ATP-binding protein with magnesium-dependent ATPase activity. We show that JFC1 specifically binds to the ATP analog 8-azido-[alpha-(32)P]ATP....
4.
Babior B
IUBMB Life
. 2001 May;
50(4-5):267-9.
PMID: 11327320
The best known NADPH oxidase is that of phagocytes-neutrophils and monocytes. In these cells, the enzyme manufactures large quantities of O2- and other reactive oxidants that are used for the...
5.
Schneider S, Fung V, Palmblad J, Babior B
Inflammation
. 2001 Apr;
25(1):17-23.
PMID: 11293662
Fish oils are known for their anti-inflammatory effects. In this paper we investigated the influence of eicosapentaenoic acid and docosahexaenoic acid (omega-3 fatty acids), as well as docosapentaenoic acid, a...
6.
McAdara Berkowitz J, Catz S, Johnson J, Ruedi J, Thon V, Babior B
J Biol Chem
. 2001 Mar;
276(22):18855-62.
PMID: 11278853
We have employed a yeast two-hybrid system to screen a B lymphoblast-derived cDNA library, searching for regulatory components of the NADPH oxidase. Using as bait the C-terminal half of p67(phox),...
7.
Dang P, Cross A, Babior B
Proc Natl Acad Sci U S A
. 2001 Mar;
98(6):3001-5.
PMID: 11248021
Activation of the phagocyte NADPH oxidase complex requires the assembly of the cytosolic factors p47(PHOX), p67(PHOX), p40(PHOX), and Rac1 or Rac2, with the membrane-bound cytochrome b(558). Whereas the interaction of...
8.
Babior B
Am J Med
. 2000 Aug;
109(1):33-44.
PMID: 10936476
Neutrophils and other phagocytes manufacture O(2)(-) (superoxide) by the one-electron reduction of oxygen at the expense of NADPH. Most of the O(2)(-) reacts with itself to form H(2)O(2) (hydrogen peroxide)....
9.
Mutomba M, Yuan H, Konyavko M, Adachi S, Yokoyama C, ESSER V, et al.
FEBS Lett
. 2000 Aug;
478(1-2):19-25.
PMID: 10922462
L-Carnitine facilitates the transport of fatty acids into the mitochondrial matrix where they are used for energy production. Recent studies have shown that L-carnitine is capable of protecting the heart...
10.
Dang P, Johnson J, Babior B
Biochemistry
. 2000 Mar;
39(11):3069-75.
PMID: 10715128
The nicotinamide adenine dinucleotide phosphate (NADPH) binding site of the NADPH oxidase complex is believed to be located on the beta, subunit of cytochrome b558. However, our previous studies showed...