B J Nicholson
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Explore the profile of B J Nicholson including associated specialties, affiliations and a list of published articles.
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51
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1419
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Recent Articles
1.
Toloue M, Woolwine Y, Karcz J, Kasperek E, Nicholson B, Skerrett I
Cell Commun Adhes
. 2008 Jul;
15(1):95-105.
PMID: 18649182
Through cysteine-scanning mutagenesis, the authors have compared sites within the transmembrane domains of two connexins, one from the alpha-class (Cx50) and one from the beta-class (Cx32), where amino acid substitution...
2.
Chandrasekhar A, Merritt M, Huh S, Nicholson B, Zucker S
Cell Commun Adhes
. 2005 Oct;
11(2-4):103-19.
PMID: 16194879
Gap junctions, composed of connexins, have been shown to suppress transformation in a variety of malignancies and transformed cell types. In addition, transforming factors such as the src oncogene have...
3.
Skerrett I, Di W, Kasperek E, Kelsell D, Nicholson B
FASEB J
. 2004 Mar;
18(7):860-2.
PMID: 15033936
Mutations in the gene GJB2, encoding the gap junction protein Connexin26 (Cx26), are the most prevalent cause of inherited hearing loss, and Cx26M34T was one of the first mutations linked...
4.
Zucker S, Nicholson B
Curr Drug Targets
. 2002 Nov;
3(6):441-53.
PMID: 12448696
Intercellular communication through gap junctions is essential for the regulation of normal cellular processes. In the diseased state, however, gap junctions may be decreased, inappropriately expressed, or constitutively expressed in...
5.
Skerrett I, Aronowitz J, Shin J, Cymes G, Kasperek E, Cao F, et al.
J Cell Biol
. 2002 Oct;
159(2):349-60.
PMID: 12403817
Gap junctions represent a ubiquitous and integral part of multicellular organisms, providing the only conduit for direct exchange of nutrients, messengers and ions between neighboring cells. However, at the molecular...
6.
Gong X, Nicholson B
Cell Commun Adhes
. 2002 Jun;
8(4-6):187-92.
PMID: 12064586
Gap junction channels are traditionally viewed as large, nonspecific pores connecting cells. Recently the diversity in the connexin family has drawn more attention to their permeability characteristics. Several studies have...
7.
Skerrett M, Kasperek E, Cao F, Shin J, Aronowitz J, Ahmed S, et al.
Cell Commun Adhes
. 2002 Jun;
8(4-6):179-85.
PMID: 12064585
The pore-lining residues of gap junction channels determine their permeability to ions and small cellular metabolites. These residues can be identified through systematic cysteine substitution and accessibility analysis, commonly known...
8.
Skerrett I, Merritt M, Zhou L, Zhu H, Cao F, Smith J, et al.
Methods Mol Biol
. 2001 Feb;
154:225-49.
PMID: 11218651
No abstract available.
9.
Goldberg G, Bechberger J, Tajima Y, Merritt M, Omori Y, Gawinowicz M, et al.
Cancer Res
. 2000 Nov;
60(21):6018-26.
PMID: 11085522
Gap junction expression has been reported to control the growth of a variety of transformed cells. We undertook parallel analysis of connexins Cx32 and Cx43 in glioma cells, which revealed...
10.
Dermietzel R, Kremer M, Paputsoglu G, Stang A, Skerrett I, Gomes D, et al.
J Neurosci
. 2000 Nov;
20(22):8331-43.
PMID: 11069940
Electrical synapses (gap junctions) in neuronal circuits have become a major focus in the study of network properties such as synchronization and oscillation (Galarreta and Hestrin, 1999; Gibson et al.,...