H C Pitot
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Explore the profile of H C Pitot including associated specialties, affiliations and a list of published articles.
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499
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Recent Articles
1.
Dehm S, Hillman D, Sicotte H, Tan W, Gormley M, Bhargava V, et al.
Ann Oncol
. 2017 Oct;
29(2):352-360.
PMID: 29069303
Background: Genomic aberrations have been identified in metastatic castration-resistant prostate cancer (mCRPC), but molecular predictors of resistance to abiraterone acetate/prednisone (AA/P) treatment are not known. Patients And Methods: In a...
2.
Atwell T, Charboneau J, Que F, Rubin J, Lewis B, Nagorney D, et al.
Cardiovasc Intervent Radiol
. 2005 Jul;
28(4):409-21.
PMID: 16041556
Carcinoid tumors and islet cell neoplasms are neuroendocrine neoplasms with indolent patterns of growth and association with bizarre hormone syndromes. These tumors behave in a relatively protracted and predictable manner,...
3.
Fang H, Tong W, Perkins R, Shi L, Hong H, Cao X, et al.
BMC Bioinformatics
. 2005 Jul;
6 Suppl 2:S6.
PMID: 16026603
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in animal models. These types of...
4.
Alberts S, Townley P, Goldberg R, Cha S, Sargent D, Moore D, et al.
Ann Oncol
. 2003 Mar;
14(4):580-5.
PMID: 12649105
Background: This study was performed to determine the efficacy of gemcitabine and oxaliplatin in patients with advanced or metastatic pancreatic adenocarcinoma (ACA). Patients And Methods: Pancreatic ACA patients with previously...
5.
Goldberg R, Kaufmann S, Atherton P, Sloan J, Adjei A, Pitot H, et al.
Ann Oncol
. 2002 Oct;
13(10):1674-80.
PMID: 12377659
Background: Irinotecan (CPT-11) and 5-fluorouracil (5-FU)/leucovorin are active agents in colorectal cancer. A sequence-dependent synergism of SN-38 followed by 5-FU/leucovorin in vitro led us to conduct a phase I trial...
6.
Alberts S, Townley P, Goldberg R, Cha S, Moore Jr D, Krook J, et al.
Ann Oncol
. 2002 Jun;
13(4):553-7.
PMID: 12056705
Background: The study was performed to determine the maximum tolerated dose (MTD) of gemcitabine and oxaliplatin in patients with advanced or metastatic pancreatic adenocarcinoma (ACA). Patients And Methods: Pancreatic ACA...
7.
Pitot H
Dev Biol (Basel)
. 2002 Jan;
106:53-7; discussion 57-9, 143-60.
PMID: 11761267
The basic animal model for neoplastic development used by regulatory agencies is the two-year chronic bioassay developed more than 30 years ago and based on the presumed mechanism of action...
8.
Sloan J, Atherton P, Reid J, Pitot H, Erlichman C, Schaaf L
Cancer Chemother Pharmacol
. 2001 Oct;
48(3):241-9.
PMID: 11592347
Purpose: We developed limited sampling models (LSMs) for predicting the area under the curve (AUC) of irinotecan (CPT-11) and its metabolites SN-38 and SN-38 glucuronide (SN-38G). Patients And Methods: Regression...
9.
Divi R, Dragan Y, Pitot H, Poirier M
Carcinogenesis
. 2001 Sep;
22(10):1693-9.
PMID: 11577011
Administration of tamoxifen (TAM) has been shown to induce hepatocellular carcinogenesis and TAM-DNA adduct formation in rat liver. Here we present TAM-DNA adduct localization and semi-quantitation in hepatic tissue of...
10.