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Ayaka Kanai

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Articles 10
Citations 70
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Recent Articles
1.
Munekata R, Uchimura T, Araki H, Kanai A, Tanaka K, Okamoto T, et al.
Materials (Basel) . 2023 Sep; 16(18). PMID: 37763566
AgSnS (ATS) has been reported to have a band gap of 1.33 eV and is expected to be a suitable material for the light-absorbing layers of compound thin-film solar cells....
2.
Nachankar A, Oike T, Hanaoka H, Kanai A, Sato H, Yoshida Y, et al.
Cancers (Basel) . 2021 Dec; 13(24). PMID: 34944777
Carbon ion radiotherapy is an emerging cancer treatment modality that has a greater therapeutic window than conventional photon radiotherapy. To maximize the efficacy of this extremely scarce medical resource, it...
3.
Kanai A, Hanaoka H, Yamaguchi A, Mahendra I, Palangka C, Ohshima Y, et al.
Nucl Med Biol . 2021 Dec; 104-105:47-52. PMID: 34896813
Introduction: 3-[F]fluoro-α-methyl-L-tyrosine ([F]FAMT) is a promising amino acid tracer targeting L-type amino acid transporter 1 (LAT1). One concern regarding the diagnosis using [F]FAMT is the possibility of false-negative findings because...
4.
Kabe Y, Koike I, Yamamoto T, Hirai M, Kanai A, Furuhata R, et al.
Cancers (Basel) . 2021 Jul; 13(13). PMID: 34209885
Progesterone receptor membrane component 1 (PGRMC1) is highly expressed in various cancer cells and contributes to tumor progression. We have previously shown that PGRMC1 forms a unique heme-stacking functional dimer...
5.
Tsugawa H, Kabe Y, Kanai A, Sugiura Y, Hida S, Taniguchi S, et al.
PLoS Biol . 2020 Sep; 18(9):e3000813. PMID: 32991574
Short-chain fatty acids (SCFAs) produced by gastrointestinal microbiota regulate immune responses, but host molecular mechanisms remain unknown. Unbiased screening using SCFA-conjugated affinity nanobeads identified apoptosis-associated speck-like protein (ASC), an adaptor...
6.
Furuhata R, Kabe Y, Kanai A, Sugiura Y, Tsugawa H, Sugiyama E, et al.
Commun Biol . 2020 Sep; 3(1):479. PMID: 32887925
Progesterone receptor membrane associated component 1 (PGRMC1) exhibits haem-dependent dimerization on cell membrane and binds to EGF receptor and cytochromes P450 to regulate cancer proliferation and chemoresistance. However, its physiological...
7.
Kabe Y, Takemoto D, Kanai A, Hirai M, Ono Y, Akazawa S, et al.
NPJ Sci Food . 2020 Mar; 4:4. PMID: 32133417
Sesamin [(7α,7'α,8α,8'α)-3,4:3',4'-bis(methylenedioxy)-7,9':7',9-diepoxylignane] is a major lignan in sesame seeds. Sesamin is converted to the catechol metabolite, SC1 [(7α,7'α,8α,8'α)-3',4'-methylenedioxy-7,9':7',9-diepoxylignane-3,4-diol] with anti-inflammatory effects after oral administration. However, its molecular target remains unknown....
8.
Yamaguchi A, Achmad A, Hanaoka H, Heryanto Y, Bhattarai A, Ratianto , et al.
BMC Cancer . 2019 Oct; 19(1):1000. PMID: 31651282
Backgrounds: Overexpression of epidermal growth factor receptor (EGFR) has been established as a valid therapeutic target of non-small cell lung cancer (NSCLC). However, the clinical benefit of cetuximab as an...
9.
Kim J, Hyeon D, Hanzawa K, Kanai A, Kim S, Lee Y, et al.
Sci Rep . 2018 Jan; 8(1):1645. PMID: 29374237
Authors report an effect of F substitution on layered SnSe through the successful synthesis of polycrystalline SnSeF (0.000 ≤ x ≤ 0.010) by solid-state reaction. Accompanied with density functional theory...
10.
Suzuki H, Kanai A, Uehara T, Guerra Gomez F, Hanaoka H, Arano Y
Bioorg Med Chem . 2011 Dec; 20(2):978-84. PMID: 22178661
A 12-membered polyazamacrocycle, 1-oxa-4,7,10-triazacyclododecane-N,N',N″-triacetic acid (ODTA), has been reported to provide an indium chelate of net neutral charge with thermodynamic stability higher than 1,4,7,10-tetraazacyclododecane-N,N',N″,N‴-tetraacetic acid (DOTA). However, neither synthetic procedure...