Hitoshi Tsugawa
Overview
Explore the profile of Hitoshi Tsugawa including associated specialties, affiliations and a list of published articles.
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Articles
44
Citations
2032
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Recent Articles
1.
Tsugawa H, Tsubaki S, Tanaka R, Nashimoto S, Imai J, Matsuzaki J, et al.
Microbes Infect
. 2024 Jun;
26(8):105371.
PMID: 38849070
Pathobionts are commensal intestinal microbiota capable of causing systemic infections under specific conditions, such as environmental changes or aging. However, it is unclear how pathobionts are recognized by the intestinal...
2.
Tanaka R, Imai J, Sugiyama E, Tsubaki S, Hozumi K, Tsugawa H
Gut Pathog
. 2024 Jan;
16(1):6.
PMID: 38267967
Background: Adherent-invasive Escherichia coli (AIEC) is isolated from patients with Crohn's disease (CD). AIEC can invade the intestinal epithelium, suggesting that it is involved in the development and pathogenesis of...
3.
Tsugawa H, Ohki T, Tsubaki S, Tanaka R, Matsuzaki J, Suzuki H, et al.
PLoS Pathog
. 2023 Jun;
19(6):e1011139.
PMID: 37289655
Immunosenescence refers to the development of weakened and/or dysfunctional immune responses associated with aging. Several commensal bacteria can be pathogenic in immunosuppressed individuals. Although Klebsiella pneumoniae is a commensal bacterium...
4.
Matsui H, Rimbara E, Suzuki M, Tokunaga K, Suzuki H, Sano M, et al.
iScience
. 2023 May;
26(4):106522.
PMID: 37123222
, hosted by hogs, is the most prevalent gastric non- species found in humans. Recent studies have suggested that infection has caused many cases of gastric disease, but the transmission...
5.
Tanaka R, Imai J, Tsugawa H, Eap K, Yazawa M, Kaneko M, et al.
Front Microbiol
. 2023 Mar;
14:1031997.
PMID: 36910191
Background And Aim: Adherent-invasive (AIEC) has been identified as a pathobiont associated with Crohn's disease (CD), that prefers to grow in inflammatory conditions. Although the colonization by AIEC is implicated...
6.
Kabe Y, Koike I, Yamamoto T, Hirai M, Kanai A, Furuhata R, et al.
Cancers (Basel)
. 2021 Jul;
13(13).
PMID: 34209885
Progesterone receptor membrane component 1 (PGRMC1) is highly expressed in various cancer cells and contributes to tumor progression. We have previously shown that PGRMC1 forms a unique heme-stacking functional dimer...
7.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
8.
Tsugawa H, Kabe Y, Kanai A, Sugiura Y, Hida S, Taniguchi S, et al.
PLoS Biol
. 2020 Sep;
18(9):e3000813.
PMID: 32991574
Short-chain fatty acids (SCFAs) produced by gastrointestinal microbiota regulate immune responses, but host molecular mechanisms remain unknown. Unbiased screening using SCFA-conjugated affinity nanobeads identified apoptosis-associated speck-like protein (ASC), an adaptor...
9.
Furuhata R, Kabe Y, Kanai A, Sugiura Y, Tsugawa H, Sugiyama E, et al.
Commun Biol
. 2020 Sep;
3(1):479.
PMID: 32887925
Progesterone receptor membrane associated component 1 (PGRMC1) exhibits haem-dependent dimerization on cell membrane and binds to EGF receptor and cytochromes P450 to regulate cancer proliferation and chemoresistance. However, its physiological...
10.
Matsuzaki J, Tsugawa H, Suzuki H
Gut Liver
. 2020 Jan;
15(1):3-12.
PMID: 31893631
Gastric cancer remains one of the most common causes of cancer-related death worldwide, although the incidence is declining gradually. The primary risk factor for gastric cancer is infection. The Kyoto...