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Aya A M Mohammed

Explore the profile of Aya A M Mohammed including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 45
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Recent Articles
1.
Suaifan G, Mohammed A, Alkhawaja B
Molecules . 2022 Mar; 27(5). PMID: 35268759
Development of novel derivatives to rein in and fight bacteria have never been more demanding, as microbial resistance strains are alarmingly increasing. A multitude of new fluoroquinolones derivatives with an...
2.
Suaifan G, Alkhawaja B, Mohammed A
Mini Rev Med Chem . 2021 Apr; 22(4):617-628. PMID: 33888048
Coronaviruses are RNA-infective viruses that could be considered principal players in universal high-profile outbreaks, namely the Severe Acute Respiratory Syndrome (SARS, 2002-2003), the Middle East Respiratory Syndrome (MERS, 2012) and...
3.
Mohammed A, Suaifan G, Shehadeh M, Okechukwu P
Eur J Med Chem . 2020 Jul; 202:112513. PMID: 32623216
Herein we report the design, synthesis and biological evaluation of structurally modified ciprofloxacin, norfloxacin and moxifloxacin standard drugs, featuring amide functional groups at C-3 of the fluoroquinolone scaffold. In vitro...
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Suaifan G, Mohammed A
Bioorg Med Chem . 2019 Jun; 27(14):3005-3060. PMID: 31182257
Fluoroquinolones are considered one of the widely utilized antibiotics, specifically, with the recent development of newer generations such as moxifloxacin, delafloxacin and finafloxacin which possess a wider spectrum of activity...
6.
Mohammed A, Suaifan G, Shehadeh M, Okechukwu P
Drug Dev Res . 2018 Dec; 80(1):179-186. PMID: 30570767
In the quest for discovering potent antimicrobial agents with lower toxicity, we envisioned the design and synthesis of nalidixic acid-D-(+)-glucosamine conjugates. The novel compounds were synthesized and evaluated for their...