Patrick N Okechukwu
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Explore the profile of Patrick N Okechukwu including associated specialties, affiliations and a list of published articles.
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7
Citations
44
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Recent Articles
1.
Martula E, Morak-Mlodawska B, Jelen M, Okechukwu P, Balachandran A, Tehirunavukarasu P, et al.
Molecules
. 2023 Nov;
28(22).
PMID: 38005384
Many new isomeric dipyridothiazine dimers have been presented as molecules with anticancer potential. These compounds were obtained in efficient syntheses of 1,6-, 1,8-, 2,7- and 3,6-diazaphenothiazines with selected alkylaromatic linkers....
2.
Balachandran A, Siyumbwa S, Froemming G, Beata M, Malgorzata J, Lavilla Jr C, et al.
Life (Basel)
. 2023 Jun;
13(6).
PMID: 37374190
(1) The complexity of diabetes and diabetic wound healing remains a therapeutic challenge because proper and systematic wound care and management are essential to prevent chronic microbial infection and mechanical...
3.
Balachandran A, Choi S, Beata M, Malgorzata J, Froemming G, Lavilla Jr C, et al.
Molecules
. 2023 Feb;
28(3).
PMID: 36770709
1. Diabetic chronic wounds, mainly foot ulcers, constitute one of the most common complications of poorly managed diabetes mellitus. The most typical reasons are insufficient glycemic management, latent neuropathy, peripheral...
4.
Okechukwu P, Ekeuku S, Chan H, Eluri K, Froemming G
Curr Pharm Biotechnol
. 2020 Aug;
22(2):288-298.
PMID: 32744968
Background: Diabetes Mellitus (DM) is characterized by hyperglycemia (high blood glucose levels) which is due to the destruction of insulin-producing β-cells in the islets of Langerhans in the pancreas. It...
5.
Mohammed A, Suaifan G, Shehadeh M, Okechukwu P
Eur J Med Chem
. 2020 Jul;
202:112513.
PMID: 32623216
Herein we report the design, synthesis and biological evaluation of structurally modified ciprofloxacin, norfloxacin and moxifloxacin standard drugs, featuring amide functional groups at C-3 of the fluoroquinolone scaffold. In vitro...
6.
Mohammed A, Suaifan G, Shehadeh M, Okechukwu P
Drug Dev Res
. 2018 Dec;
80(1):179-186.
PMID: 30570767
In the quest for discovering potent antimicrobial agents with lower toxicity, we envisioned the design and synthesis of nalidixic acid-D-(+)-glucosamine conjugates. The novel compounds were synthesized and evaluated for their...
7.
Chang V, Okechukwu P, Teo S
Biomed Pharmacother
. 2017 Jan;
87:296-301.
PMID: 28063411
The edible red seaweed (Kappaphycus alvarezii) is one of the algae species which was found to be rich in nutrients and nutraceutical. Hence, K. alvarezii may have the ability to...