Aveline Filliol
Overview
Explore the profile of Aveline Filliol including associated specialties, affiliations and a list of published articles.
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30
Citations
1107
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Recent Articles
1.
Sugimoto A, Saito Y, Wang G, Sun Q, Yin C, Lee K, et al.
Nature
. 2025 Mar;
PMID: 40074890
Hepatic stellate cells (HSCs) have a central pathogenetic role in the development of liver fibrosis. However, their fibrosis-independent and homeostatic functions remain poorly understood. Here we demonstrate that genetic depletion...
2.
Sererols-Vinas L, Garcia-Vicien G, Ruiz-Blazquez P, Lee T, Lee Y, Gonzalez-Sanchez E, et al.
Semin Liver Dis
. 2025 Mar;
PMID: 40043738
Hepatic stellate cells (HSCs) are the liver's pericytes, and play key roles in liver homeostasis, regeneration, fibrosis and cancer. Upon injury, HSCs activate and are the main origin of myofibroblasts...
3.
Filliol A
Cell Mol Gastroenterol Hepatol
. 2024 Dec;
19(3):101437.
PMID: 39719264
No abstract available.
4.
Affo S, Filliol A, Gores G, Schwabe R
Lancet Gastroenterol Hepatol
. 2023 Jun;
8(8):748-759.
PMID: 37385282
Accumulation of fibroblasts in the premalignant or malignant liver is a characteristic feature of liver cancer, but has not been therapeutically leveraged despite evidence for pathophysiologically relevant roles in tumour...
5.
Saito Y, Yin D, Kubota N, Wang X, Filliol A, Remotti H, et al.
Gastroenterology
. 2023 Mar;
164(7):1279-1292.
PMID: 36894036
Background & Aims: Despite recent progress, long-term survival remains low for hepatocellular carcinoma (HCC). The most effective HCC therapies target the tumor immune microenvironment (TIME), and there are almost no...
6.
Su H, Yang F, Fu R, Trinh B, Sun N, Liu J, et al.
Nature
. 2023 Mar;
615(7953):E24.
PMID: 36882540
No abstract available.
7.
Filliol A, Saito Y, Nair A, Dapito D, Yu L, Ravichandra A, et al.
Nature
. 2022 Oct;
610(7931):356-365.
PMID: 36198802
Hepatocellular carcinoma (HCC), the fourth leading cause of cancer mortality worldwide, develops almost exclusively in patients with chronic liver disease and advanced fibrosis. Here we interrogated functions of hepatic stellate...
8.
Su H, Yang F, Fu R, Trinh B, Sun N, Liu J, et al.
Nature
. 2022 Oct;
610(7931):366-372.
PMID: 36198801
Pancreatic ductal adenocarcinoma (PDAC) is a highly desmoplastic, aggressive cancer that frequently progresses and spreads by metastasis to the liver. Cancer-associated fibroblasts, the extracellular matrix and type I collagen (Col...
9.
10.
Mederacke I, Filliol A, Affo S, Nair A, Hernandez C, Sun Q, et al.
Sci Transl Med
. 2022 Apr;
14(639):eabe5795.
PMID: 35385339
Fibrosis contributes to ~45% of deaths in western countries. In chronic liver disease, fibrosis is a major factor determining outcomes, but efficient antifibrotic therapies are lacking. Although platelet-derived growth factor...