Catherine Lucas-Clerc
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Explore the profile of Catherine Lucas-Clerc including associated specialties, affiliations and a list of published articles.
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16
Citations
335
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Recent Articles
1.
Filliol A, Piquet-Pellorce C, Dion S, Genet V, Lucas-Clerc C, Dantzer F, et al.
Am J Physiol Gastrointest Liver Physiol
. 2017 Jul;
313(5):G399-G409.
PMID: 28751426
Excessive or persistent inflammation and hepatocyte death are the key triggers of liver diseases. The poly(ADP-ribose) polymerase (PARP) proteins induce cell death and inflammation. Chemical inhibition of PARP activity protects...
2.
Vasseur P, Dion S, Filliol A, Genet V, Lucas-Clerc C, Jean-Philippe G, et al.
Oncotarget
. 2017 Jun;
8(30):48563-48574.
PMID: 28611297
Interleukin (IL)-33 has been recently reported to be strongly pro-fibrogenic in various models of liver disease. Our aim was to study the role of endogenous IL-33 in a diet-induced model...
3.
Carriere V, Arshad M, Le Seyec J, Lefevre B, Farooq M, Jan A, et al.
Mediators Inflamm
. 2017 Jun;
2017:1359064.
PMID: 28607531
The alarmin IL-33 has been described to be upregulated in human and murine viral hepatitis. However, the role of endogenous IL-33 in viral hepatitis remains obscure. We aimed to decipher...
4.
Filliol A, Piquet-Pellorce C, Raguenes-Nicol C, Dion S, Farooq M, Lucas-Clerc C, et al.
J Hepatol
. 2017 Jan;
66(6):1205-1213.
PMID: 28088582
Background & Aims: The severity of liver diseases is exacerbated by the death of hepatocytes, which can be induced by the sensing of pathogen associated molecular patterns (PAMPs) derived from...
5.
Filliol A, Piquet-Pellorce C, Le Seyec J, Farooq M, Genet V, Lucas-Clerc C, et al.
Cell Death Dis
. 2016 Nov;
7(11):e2462.
PMID: 27831558
Cell death of hepatocytes is a prominent characteristic in the pathogenesis of liver disease, while hepatolysis is a starting point of inflammation in hepatitis and loss of hepatic function. However,...
6.
Noel G, Arshad M, Filliol A, Genet V, Rauch M, Lucas-Clerc C, et al.
Am J Physiol Gastrointest Liver Physiol
. 2016 Jun;
311(2):G313-23.
PMID: 27340126
The IL-33/ST2 axis plays a protective role in T-cell-mediated hepatitis, but little is known about the functional impact of endogenous IL-33 on liver immunopathology. We used IL-33-deficient mice to investigate...
7.
Tabet E, Genet V, Tiaho F, Lucas-Clerc C, Gelu-Simeon M, Piquet-Pellorce C, et al.
Toxicol Lett
. 2016 Feb;
255:1-10.
PMID: 26853152
Chronic liver damage due to viral or chemical agents leads to a repair process resulting in hepatic fibrosis. Fibrosis may lead to cirrhosis, which may progress to liver cancer or...
8.
Arshad M, Guihard P, Danger Y, Noel G, Le Seyec J, Boutet M, et al.
Am J Physiol Gastrointest Liver Physiol
. 2015 Aug;
309(7):G542-53.
PMID: 26251474
Interleukin (IL)-33 is crucially involved in liver pathology and drives hepatoprotective functions. However, the regulation of IL-33 by cytokines of the IL-6 family, including oncostatin M (OSM) and IL-6, is...
9.
Arshad M, Piquet-Pellorce C, Filliol A, LHelgoualch A, Lucas-Clerc C, Jouan-Lanhouet S, et al.
J Mol Med (Berl)
. 2015 Mar;
93(8):867-78.
PMID: 25747661
Unlabelled: Interleukin-33 (IL-33), a cytokine belonging to the IL-1 family, is crucially involved in inflammatory pathologies including liver injury and linked to various modes of cell death. However, a link...
10.
Arshad M, Patrat-Delon S, Piquet-Pellorce C, LHelgoualch A, Rauch M, Genet V, et al.
PLoS One
. 2013 Sep;
8(9):e74278.
PMID: 24058536
The IL-33/ST2 axis is known to be involved in liver pathologies. Although, the IL-33 levels increased in sera of viral hepatitis patients in human, the cellular sources of IL-33 in...