Ave Eesmaa
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Explore the profile of Ave Eesmaa including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
211
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0
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Recent Articles
1.
Kovaleva V, Yu L, Ivanova L, Shpironok O, Nam J, Eesmaa A, et al.
Cell Rep
. 2023 Feb;
42(2):112066.
PMID: 36739529
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-located protein with cytoprotective effects in neurons and pancreatic β cells in vitro and in models of neurodegeneration and diabetes in ...
2.
Eesmaa A, Yu L, Goos H, Danilova T, Noges K, Pakarinen E, et al.
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012764
Cerebral dopamine neurotrophic factor (CDNF) is a neurotrophic factor that has beneficial effects on dopamine neurons in both in vitro and in vivo models of Parkinson's disease (PD). CDNF was...
3.
Albert K, Raymundo D, Panhelainen A, Eesmaa A, Shvachiy L, Araujo G, et al.
Mol Ther
. 2021 May;
29(9):2821-2840.
PMID: 33940158
A molecular hallmark in Parkinson's disease (PD) pathogenesis are α-synuclein aggregates. Cerebral dopamine neurotrophic factor (CDNF) is an atypical growth factor that is mostly resident in the endoplasmic reticulum but...
4.
Eesmaa A, Yu L, Goos H, Noges K, Kovaleva V, Hellman M, et al.
J Biol Chem
. 2021 Jan;
296:100295.
PMID: 33460650
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-stress-regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and...
5.
Yagi T, Asada R, Kanekura K, Eesmaa A, Lindahl M, Saarma M, et al.
iScience
. 2020 Dec;
23(12):101810.
PMID: 33299977
Endoplasmic reticulum (ER) stress is known to induce pro-inflammatory response and ultimately leads to cell death. Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an ER-localized protein whose expression and secretion is...
6.
Garea-Rodriguez E, Eesmaa A, Lindholm P, Schlumbohm C, Konig J, Meller B, et al.
PLoS One
. 2016 Feb;
11(2):e0149776.
PMID: 26901822
Cerebral dopamine neurotrophic factor (CDNF) belongs to a newly discovered family of evolutionarily conserved neurotrophic factors. We demonstrate for the first time a therapeutic effect of CDNF in a unilateral...
7.
Sepp M, Kannike K, Eesmaa A, Urb M, Timmusk T
PLoS One
. 2011 Jul;
6(7):e22138.
PMID: 21789225
Background: Transcription factor 4 (TCF4 alias ITF2, E2-2, ME2 or SEF2) is a ubiquitous class A basic helix-loop-helix protein that binds to E-box DNA sequences (CANNTG). While involved in the...