Aurelien Dugourd
Overview
Explore the profile of Aurelien Dugourd including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
1557
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dimitrov D, Schafer P, Farr E, Rodriguez-Mier P, Lobentanzer S, Badia-I-Mompel P, et al.
Nat Cell Biol
. 2024 Sep;
26(9):1613-1622.
PMID: 39223377
The growing availability of single-cell and spatially resolved transcriptomics has led to the development of many approaches to infer cell-cell communication, each capturing only a partial view of the complex...
2.
Farr E, Dimitrov D, Schmidt C, Turei D, Lobentanzer S, Dugourd A, et al.
Brief Bioinform
. 2024 Jul;
25(4).
PMID: 39038934
From the catalytic breakdown of nutrients to signaling, interactions between metabolites and proteins play an essential role in cellular function. An important case is cell-cell communication, where metabolites, secreted into...
3.
Gegner H, Naake T, Aljakouch K, Dugourd A, Kliewer G, Muller T, et al.
Clin Proteomics
. 2024 Jul;
21(1):49.
PMID: 38969985
Understanding the interplay of the proteome and the metabolome helps to understand cellular regulation and response. To enable robust inferences from such multi-omics analyses, we introduced and evaluated a workflow...
4.
Niarakis A, Ostaszewski M, Mazein A, Kuperstein I, Kutmon M, Gillespie M, et al.
Front Immunol
. 2024 Feb;
14:1282859.
PMID: 38414974
Introduction: The COVID-19 Disease Map project is a large-scale community effort uniting 277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic content describing SARS-CoV-2-host interactions and develop...
5.
Erickson E, You I, Perry G, Dugourd A, Donovan K, Crafter C, et al.
Sci Signal
. 2024 Feb;
17(825):eadf2670.
PMID: 38412255
More than 50% of human tumors display hyperactivation of the serine/threonine kinase AKT. Despite evidence of clinical efficacy, the therapeutic window of the current generation of AKT inhibitors could be...
6.
Billing A, Kim Y, Gullaksen S, Schrage B, Raabe J, Hutzfeldt A, et al.
Circulation
. 2023 Dec;
149(11):860-884.
PMID: 38152989
Background: SGLT2 (sodium-glucose cotransporter 2) inhibitors (SGLT2i) can protect the kidneys and heart, but the underlying mechanism remains poorly understood. Methods: To gain insights on primary effects of SGLT2i that...
7.
Kaesler N, Cheng M, Nagai J, OSullivan J, Peisker F, Bindels E, et al.
Sci Adv
. 2023 Nov;
9(47):eadj4846.
PMID: 38000021
Patients with advanced chronic kidney disease (CKD) mostly die from sudden cardiac death and recurrent heart failure. The mechanisms of cardiac remodeling are largely unclear. To dissect molecular and cellular...
8.
Salovska B, Gao E, Muller-Dott S, Li W, Chacon Cordon C, Wang S, et al.
Clin Transl Med
. 2023 Feb;
13(2):e1179.
PMID: 36781298
Background: The biguanide drug metformin is a safe and widely prescribed drug for type 2 diabetes. Interestingly, hundreds of clinical trials have been set to evaluate the potential role of...
9.
Badia-I-Mompel P, Velez Santiago J, Braunger J, Geiss C, Dimitrov D, Muller-Dott S, et al.
Bioinform Adv
. 2023 Jan;
2(1):vbac016.
PMID: 36699385
Summary: Many methods allow us to extract biological activities from omics data using information from prior knowledge resources, reducing the dimensionality for increased statistical power and better interpretability. Here, we...
10.
Sousa A, Dugourd A, Memon D, Petursson B, Petsalaki E, Saez-Rodriguez J, et al.
Mol Syst Biol
. 2023 Jan;
19(3):e10631.
PMID: 36688815
Genetic alterations in cancer cells trigger oncogenic transformation, a process largely mediated by the dysregulation of kinase and transcription factor (TF) activities. While the mutational profiles of thousands of tumours...