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Aurelie Cazet

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Articles 18
Citations 596
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Recent Articles
1.
Filipe E, Velayuthar S, Philp A, Nobis M, Latham S, Parker A, et al.
Adv Sci (Weinh) . 2024 Apr; 11(23):e2307963. PMID: 38602451
In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary tumor biomechanics on the latter...
2.
Thankamony A, Murali R, Karthikeyan N, Varghese B, Teo W, McFarland A, et al.
Biomolecules . 2020 Sep; 10(9). PMID: 32911668
The basic helix-loop-helix (bHLH) transcription factors inhibitor of differentiation 1 () and inhibitor of differentiation 3 (referred to as ) have an important role in maintaining the cancer stem cell...
3.
Bennett D, Cazet A, Charest J, Contessa J
Glycoconj J . 2018 Apr; 35(3):265-274. PMID: 29671116
N-linked glycosylation (NLG) is a co-translational modification that is essential for the folding, stability, and trafficking of transmembrane (TM) and secretory glycoproteins. Efficient NLG requires the stepwise synthesis and en...
4.
Junankar S, Baker L, Roden D, Nair R, Elsworth B, Gallego-Ortega D, et al.
Nat Commun . 2015 Mar; 6:6548. PMID: 25813983
Basal-like breast cancer (BLBC) is a heterogeneous disease with poor prognosis; however, its cellular origins and aetiology are poorly understood. In this study, we show that inhibitor of differentiation 4...
5.
Cazet A, Charest J, Bennett D, Lopez Sambrooks C, Contessa J
PLoS One . 2014 Oct; 9(10):e110345. PMID: 25314669
Asparagine-linked glycosylation is an endoplasmic reticulum co- and post-translational modification that enables the transit and function of receptor tyrosine kinase (RTK) glycoproteins. To gain insight into the regulatory role of...
6.
Van Slambrouck S, Groux-Degroote S, Krzewinski-Recchi M, Cazet A, Delannoy P, Steelant W
Biosci Rep . 2014 Aug; 34(5). PMID: 25137483
Complex interplays among proteins, lipids and carbohydrates can alter the phenotype and are suggested to have a crucial role in tumour metastasis. Our previous studies indicated that a complex of...
7.
Hui M, Cazet A, Nair R, Watkins D, OToole S, Swarbrick A
Breast Cancer Res . 2013 Apr; 15(2):203. PMID: 23547970
Despite the progress achieved in breast cancer screening and therapeutic innovations, the basal-like subtype of breast cancer (BLBC) still represents a particular clinical challenge. In order to make an impact...
8.
OToole S, Beith J, Millar E, West R, McLean A, Cazet A, et al.
J Clin Pathol . 2013 Feb; 66(6):530-42. PMID: 23436929
Outcomes have improved significantly for many women diagnosed with breast cancer. For the heterogeneous group of tumours lacking expression of the oestrogen, progesterone and HER2 receptors, 'triple negative' breast cancers...
9.
Steenackers A, Vanbeselaere J, Cazet A, Bobowski M, Rombouts Y, Colomb F, et al.
Molecules . 2012 Aug; 17(8):9559-72. PMID: 22885356
Glycosphingolipids from the ganglio-series are usually classified in four series according to the presence of 0 to 3 sialic acid residues linked to lactosylceramide. The transfer of sialic acid is...
10.
Cazet A, Bobowski M, Rombouts Y, Lefebvre J, Steenackers A, Popa I, et al.
Glycobiology . 2012 Feb; 22(6):806-16. PMID: 22301273
We have recently established and characterized cellular clones deriving from MDA-MB-231 breast cancer cells that express the human G(D3) synthase (GD3S), the enzyme that controls the biosynthesis of b- and...