Sophie Groux-Degroote
Overview
Explore the profile of Sophie Groux-Degroote including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
678
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Recent Articles
1.
Groux-Degroote S, Martin K, Yakayama N, Yamakawa N, Coddeville B, Guerardel Y, et al.
Cytotherapy
. 2025 Feb;
PMID: 39895443
Prior studies have indicated that human embryonic stem cells can be distinguished from those of other mammals based on variable expression of a class of membrane glycolipids known as glycosphingolipids...
2.
Kasprowicz A, Cavdarli S, Delannoy P, Le Guezennec X, Defebvre C, Spriet C, et al.
Mol Cell Biochem
. 2024 Oct;
PMID: 39395135
O-acetylated GD2 (OAcGD2) is a cancer-related antigen that is currently being explored for therapeutic use. Exploring the intricate mechanisms behind OAcGD2 synthesis in cancer cells has long been a challenge....
3.
Cogez V, Vicogne D, Schulz C, Portier L, Venturi G, de Ruyck J, et al.
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835549
The Sd carbohydrate epitope and its biosynthetic B4GALNT2 enzyme are expressed in the healthy colon and down-regulated to variable extents in colon cancer. The human gene drives the expression of...
4.
Yamaguchi E, Komura N, Tanaka H, Imamura A, Ishida H, Groux-Degroote S, et al.
Glycoconj J
. 2023 Jan;
40(2):247-257.
PMID: 36701103
Ganglioside GD2 is associated with the proliferation and migration of breast cancer cells. However, the precise role of GD2 is unclear because its tendency to form dynamic and transient domains...
5.
Wavelet-Vermuse C, Groux-Degroote S, Vicogne D, Cogez V, Venturi G, Trinchera M, et al.
Biochim Biophys Acta Gene Regul Mech
. 2021 Sep;
1864(11-12):194747.
PMID: 34500083
Background: The Sd antigen and corresponding biosynthetic enzyme B4GALNT2 are primarily expressed in normal colonic mucosa and are down-regulated to a variable degree in colon cancer tissues. Although their expression...
6.
Groux-Degroote S, Vicogne D, Cogez V, Schulz C, Harduin-Lepers A
Chembiochem
. 2021 Aug;
22(24):3381-3390.
PMID: 34397142
The Sd carbohydrate antigen and the corresponding biosynthetic enzyme B4GALNT2 are primarily expressed in human normal colonic mucosa and are down-regulated to variable degrees in colon cancer. On the other...
7.
Cavdarli S, Schroter L, Albers M, Baumann A, Vicogne D, Le Doussal J, et al.
Cells
. 2021 Jul;
10(6).
PMID: 34208013
The -acetylated form of GD2, almost exclusively expressed in cancerous tissues, is considered to be a promising therapeutic target for neuroectoderm-derived tumors, especially for breast cancer. Our recent data have...
8.
Groux-Degroote S, Delannoy P
Int J Mol Sci
. 2021 Jul;
22(11).
PMID: 34200284
Aberrant expression of glycosphingolipids is a hallmark of cancer cells and is associated with their malignant properties. Disialylated gangliosides GD2 and GD3 are considered as markers of neuroectoderm origin in...
9.
Groux-Degroote S, Foulquier F, Cavdarli S, Delannoy P
Med Sci (Paris)
. 2021 Jun;
37(6-7):609-617.
PMID: 34180820
Glycosylation is one of the essential modifications of proteins and lipids. It is carried out mainly in the endoplasmic reticulum and Golgi apparatus, and requires a specific molecular machinery associating...
10.
Delannoy C, Huang C, Coddeville B, Chen J, Mouajjah D, Groux-Degroote S, et al.
Mol Omics
. 2020 Apr;
16(4):345-354.
PMID: 32270793
Macrophage glycosylation is essential to initiate the host-immune defense but may also be targeted by pathogens to promote infection. Indeed, the alteration of the cell-surface glycosylation status may affect the...