Atsuko Shirai
Overview
Explore the profile of Atsuko Shirai including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
588
Followers
0
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Recent Articles
1.
Wajima T, Hara N, Tanaka E, Shirai A, Uchiya K
Biol Pharm Bull
. 2025 Feb;
48(1):60-64.
PMID: 39894556
Haemophilus influenzae presents significant concerns regarding antimicrobial resistance. The circumstances surrounding H. influenzae have been changing owing to changes in antimicrobial usage. In the present study, to determine the current...
2.
Wajima T, Hara N, Tanaka E, Shirai A, Uchiya K
Microb Drug Resist
. 2024 May;
30(8):350-352.
PMID: 38770769
No abstract available.
3.
Balan S, Iwayama Y, Ohnishi T, Fukuda M, Shirai A, Yamada A, et al.
Mol Psychiatry
. 2021 Jul;
26(12):7550-7559.
PMID: 34262135
Recent evidence has documented the potential roles of histone-modifying enzymes in autism-spectrum disorder (ASD). Aberrant histone H3 lysine 9 (H3K9) dimethylation resulting from genetic variants in histone methyltransferases is known...
4.
Tanaka E, Wajima T, Hara N, Shirai A, Shibata M, Shiro H, et al.
J Med Microbiol
. 2020 Jan;
69(2):239-243.
PMID: 31961789
Recently, a clone with low susceptibility to quinolones emerged in paediatric patients in Japan. Isolates of this clone survived for a long time when exposed to the therapeutic concentration of...
5.
Oya E, Nakagawa R, Yoshimura Y, Tanaka M, Nishibuchi G, Machida S, et al.
EMBO Rep
. 2019 Aug;
20(10):e48111.
PMID: 31468675
The methylation of histone H3 at lysine 9 (H3K9me), performed by the methyltransferase Clr4/SUV39H, is a key event in heterochromatin assembly. In fission yeast, Clr4, together with the ubiquitin E3...
6.
Tanaka E, Hara N, Wajima T, Ochiai S, Seyama S, Shirai A, et al.
J Glob Antimicrob Resist
. 2019 Feb;
18:104-108.
PMID: 30753907
Background: The use of non-β-lactam agents has increased in Japan due to the prevalence of β-lactam-resistant pathogens. This study aimed to clarify the recent trend of antimicrobial susceptibility and molecular...
7.
Hara N, Wajima T, Seyama S, Tanaka E, Shirai A, Shibata M, et al.
J Infect Chemother
. 2018 Nov;
25(5):385-387.
PMID: 30482699
In paediatric patients, β-lactams and macrolides are widely used to treat acute otitis media and sinusitis, which are often caused by either Streptococcus pneumoniae or Haemophilus influenzae. However, resistant isolates...
8.
Matsuyama A, Shirai A, Yoshida M
Methods Mol Biol
. 2018 Feb;
1721:125-133.
PMID: 29423853
Immunoprecipitation is one of the most important and widely used techniques for the detection and purification of a protein of interest. Thanks to highly specific interaction between antigen and antibody,...
9.
Shirai A, Kawaguchi T, Shimojo H, Muramatsu D, Ishida-Yonetani M, Nishimura Y, et al.
Elife
. 2017 Sep;
6.
PMID: 28874256
No abstract available.
10.
Shirai A, Kawaguchi T, Shimojo H, Muramatsu D, Ishida-Yonetani M, Nishimura Y, et al.
Elife
. 2017 Aug;
6.
PMID: 28760201
SUV39H is the major histone H3 lysine 9 (H3K9)-specific methyltransferase that targets pericentric regions and is crucial for assembling silent heterochromatin. SUV39H recognizes trimethylated H3K9 (H3K9me3) via its chromodomain (CD),...