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Astrid Walrant

Explore the profile of Astrid Walrant including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 381
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Recent Articles
1.
Al Yaman K, Al Bardawil S, Ostojic M, Walrant A, Dole F, Villette S, et al.
Bioconjug Chem . 2024 Nov; 35(12):1900-1912. PMID: 39556423
Controlling passive diffusion through an amphiphilic membrane is a key factor for the development of future smart generations of drug delivery systems. It also plays a crucial role in understanding...
2.
Cayrou C, Walrant A, Ravault D, Guitot K, Noinville S, Sagan S, et al.
Chem Commun (Camb) . 2024 Jul; 60(65):8609-8612. PMID: 39046095
The development and the use of fluorinated polyproline-type II (PPII) foldamers are still underexplored. Herein, trifluoromethyl pseudoprolines have been incorporated into polyproline backbones without affecting their PPII helicity. The ability...
3.
Walrant A, Sachon E
Mass Spectrom Rev . 2024 Apr; PMID: 38576378
Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on...
4.
Cardon S, Hervis Y, Bolbach G, Lopin-Bon C, Jacquinet J, Illien F, et al.
Nat Commun . 2023 Apr; 14(1):1998. PMID: 37032404
Engrailed2 (En2) is a transcription factor that transfers from cell to cell through unconventional pathways. The poorly understood internalization mechanism of this cationic protein is proposed to require an initial...
5.
Khemaissa S, Walrant A, Sagan S
Q Rev Biophys . 2022 Aug; 55:e10. PMID: 35979810
Trp is unique among the amino acids since it is involved in many different types of noncovalent interactions such as electrostatic and hydrophobic ones, but also in π-π, π-cation, π-anion...
6.
Bechtella L, Chalouhi E, Milan Rodriguez P, Cosset M, Ravault D, Illien F, et al.
ACS Chem Biol . 2022 May; 17(6):1427-1439. PMID: 35608167
Cell-penetrating peptides cross cell membranes through various parallel internalization pathways. Herein, we analyze the role of the negatively charged lipid phosphatidylinositol-4,5-bisphosphate (PI(4,5)P) in the internalization of Penetratin. Contributions of both...
7.
Walrant A, Illien F, Sagan S, Rodriguez N
Methods Mol Biol . 2021 Nov; 2383:143-152. PMID: 34766287
Fluorescence-based methods are widely used to detect crossing of peptides across model or biological membranes. For membrane-active peptides, i.e., peptides that have strong membrane tropism, fluorescence experiments must be accompanied...
8.
Walrant A, Sachon E
Bioconjug Chem . 2021 Jun; 32(8):1503-1514. PMID: 34160213
Membranotropic peptides is a class of peptides that exert their biological action at the level of cell membranes. Understanding how they interact with their different membrane binding partners (lipids, proteins,...
9.
Dobramysl U, Jarsch I, Inoue Y, Shimo H, Richier B, Gadsby J, et al.
J Cell Biol . 2021 Mar; 220(4). PMID: 33740033
Assemblies of actin and its regulators underlie the dynamic morphology of all eukaryotic cells. To understand how actin regulatory proteins work together to generate actin-rich structures such as filopodia, we...
10.