Astrid Walrant
Overview
Explore the profile of Astrid Walrant including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
381
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Recent Articles
11.
Sachon E, Walrant A, Sagan S, Cribier S, Rodriguez N
Arch Biochem Biophys
. 2021 Jan;
699:108751.
PMID: 33421380
Antimicrobial and cell-penetrating peptides have been the object of extensive studies for more than 60 years. Initially these two families were studied separately, and more recently parallels have been drawn....
12.
Masuda T, Hirose H, Baba K, Walrant A, Sagan S, Inagaki N, et al.
Bioconjug Chem
. 2020 May;
31(6):1611-1615.
PMID: 32378884
Membrane curvature plays a pivotal role in cellular life, including cellular uptake and membrane trafficking. The modulation of membrane curvature provides a novel means of manipulating cellular events. In this...
13.
Figueira T, Domingues M, Illien F, Cadima-Couto I, Todorovski T, Andreu D, et al.
ACS Infect Dis
. 2019 Dec;
6(2):224-236.
PMID: 31855415
We have developed a nanocarrier consisting of large unilamellar vesicles (LUVs) for combined delivery of two human immunodeficiency virus type 1 (HIV-1) entry inhibitors, enfuvirtide (ENF) and protoporphyrin IX (PPIX)....
14.
Walrant A, Bauza A, Girardet C, Alves I, Lecomte S, Illien F, et al.
Biochim Biophys Acta Biomembr
. 2019 Nov;
1862(2):183098.
PMID: 31676372
Cell-penetrating peptides (CPPs) internalization occurs both by endocytosis and direct translocation through the cell membrane. These different entry routes suggest that molecular partners at the plasma membrane, phospholipids or glycosaminoglycans...
15.
Bechtella L, Kirschbaum C, Cosset M, Clodic G, Matheron L, Bolbach G, et al.
Anal Chem
. 2019 Jun;
91(14):9102-9110.
PMID: 31251038
Affinity photo-cross-linking coupled to mass spectrometry, using benzophenone (Bzp)-functionalized peptides, was used to study the noncovalent interactions of cell-penetrating peptides and lipid membranes. Using biomimetic lipid vesicles composed of saturated...
16.
Kress T, Walrant A, Bodenhausen G, Kurzbach D
J Phys Chem Lett
. 2019 Mar;
10(7):1523-1529.
PMID: 30864805
We introduce a method for the detection of weak interactions of small molecules such as metabolites or medicaments that contain deuterated methyl groups with proteins in solution. The technique relies...
17.
Cardon S, Sachon E, Carlier L, Drujon T, Walrant A, Aleman-Navarro E, et al.
PLoS One
. 2018 Oct;
13(10):e0205727.
PMID: 30325956
The occurrence of nosocomial infections has been on the rise for the past twenty years. Notably, infections caused by the Gram-positive bacteria Staphylococcus aureus represent a major clinical problem, as...
18.
Walrant A, Cardon S, Burlina F, Sagan S
Acc Chem Res
. 2017 Nov;
50(12):2968-2975.
PMID: 29172443
Living organisms have to maintain a stable balance in molecules and ions in the changing environment in which they are living, a process known as homeostasis. At the level of...
19.
Derde M, Vie V, Walrant A, Sagan S, Lechevalier V, Guerin-Dubiard C, et al.
Biopolymers
. 2017 Sep;
107(12).
PMID: 28944959
Increasing bacterial resistance towards antibiotics has stimulated research for novel antimicrobials. Proteins acting on bacterial membranes could be a solution. Lysozyme has been proven active against E. coli by disruption...
20.
Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature
Daste F, Walrant A, Holst M, Gadsby J, Mason J, Lee J, et al.
J Cell Biol
. 2017 Sep;
216(11):3745-3765.
PMID: 28923975
The conditional use of actin during clathrin-mediated endocytosis in mammalian cells suggests that the cell controls whether and how actin is used. Using a combination of biochemical reconstitution and mammalian...