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Arun Upadhyay

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Articles 52
Citations 740
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Recent Articles
11.
Anand U, Dey A, Chandel A, Sanyal R, Mishra A, Pandey D, et al.
Genes Dis . 2023 Jul; 10(4):1367-1401. PMID: 37397557
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and produce aggressive malignancies that causes millions of deaths every year. With the new understanding of the molecular...
12.
Singh S, Joshi V, Upadhyay A
Biosci Rep . 2023 Jun; 43(10). PMID: 37335084
Amyloids are high-order proteinaceous formations deposited in both intra- and extracellular spaces. These aggregates have tendencies to deregulate cellular physiology in multiple ways; for example, altered metabolism, mitochondrial dysfunctions, immune...
13.
Amanullah A, Upadhyay A, Dhiman R, Singh S, Kumar A, Ahirwar D, et al.
Cancers (Basel) . 2022 Sep; 14(18). PMID: 36139546
Diclofenac is a highly prescribed non-steroidal anti-inflammatory drug (NSAID) that relieves inflammation, pain, fever, and aches, used at different doses depending on clinical conditions. This drug inhibits cyclooxygenase-1 and cyclooxygenase-2...
14.
Upadhyay A, Vassar R, Savas J
J Vis Exp . 2022 May; (182). PMID: 35575522
Proteinaceous fibrillar inclusions are key pathological hallmarks of multiple neurodegenerative diseases. In the early stages of Alzheimer's disease (AD), amyloid-beta peptides form protofibrils in the extracellular space, which act as...
15.
Upadhyay A
Acta Pharm Sin B . 2021 Nov; 11(10):2995-3014. PMID: 34729300
Cells have different sets of molecules for performing an array of physiological functions. Nucleic acids have stored and carried the information throughout evolution, whereas proteins have been attributed to performing...
16.
Sundaria N, Upadhyay A, Prasad A, Prajapati V, Poluri K, Mishra A
Mech Ageing Dev . 2021 Sep; 200:111574. PMID: 34562507
Cellular homeostasis is regulated by the protein quality control (PQC) machinery, comprising multiple chaperones and enzymes. Studies suggest that the loss of the PQC mechanisms in neurons may lead to...
17.
Upadhyay A
Genes Dis . 2021 Jul; 8(5):655-661. PMID: 34291136
Cancer is a disease of altered signaling and metabolism, causing uncontrolled division and survival of transformed cells. A host of molecules, factors, and conditions have been designated as underlying causes...
18.
Prusty D, Gupta N, Upadhyay A, Dar A, Naik B, Kumar N, et al.
Infect Genet Evol . 2021 Jul; 93:104987. PMID: 34216796
There has been a consistent rise in malaria cases in the last few years. The existing malaria control measures are challenged by insecticide resistance in the mosquito vector, drug résistance...
19.
Jakhmola S, Upadhyay A, Jain K, Mishra A, Jha H
J Neuroimmunol . 2021 Jun; 358:577636. PMID: 34174587
Herpesviruses like Epstein-Barr virus, human herpesvirus (HHV)-6, HHV-1, VZV, and human endogenous retroviruses, have an age-old clinical association with multiple sclerosis (MS). MS is an autoimmune disease of the nervous...
20.
Upadhyay A, Amanullah A, Joshi V, Dhiman R, Prajapati V, Poluri K, et al.
Drug Metab Rev . 2021 Apr; 53(1):100-121. PMID: 33820460
Ibuprofen is a classical nonsteroidal anti-inflammatory drug (NSAID) highly prescribed to reduce acute pain and inflammation under an array of conditions, including rheumatoid arthritis, osteoarthritis, dysmenorrhea, and gout. Ibuprofen acts...