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Arun Everest-Dass

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Articles 21
Citations 318
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Recent Articles
11.
De Oliveira D, Bohlmann L, Conroy T, Jen F, Everest-Dass A, Hansford K, et al.
Sci Transl Med . 2020 Nov; 12(570). PMID: 33208501
The emergence of polymyxin resistance in carbapenem-resistant and extended-spectrum β-lactamase (ESBL)-producing bacteria is a critical threat to human health, and alternative treatment strategies are urgently required. We investigated the ability...
12.
Vyas H, Indraratna A, Everest-Dass A, Packer N, De Oliveira D, Ranson M, et al.
Antibiotics (Basel) . 2020 Nov; 9(11). PMID: 33158121
Group A (GAS) causes 700 million infections and accounts for half a million deaths per year. Antibiotic treatment failure rates of 20-40% have been observed. The role host cell glycans...
13.
Shewell L, Day C, Jen F, Haselhorst T, Atack J, Reijneveld J, et al.
Sci Adv . 2020 Jun; 6(21):eaaz4926. PMID: 32494740
Cholesterol-dependent cytolysins (CDCs) form pores in cholesterol-rich membranes, but cholesterol alone is insufficient to explain their cell and host tropism. Here, we show that all eight major CDCs have high-affinity...
14.
De Leoz M, Duewer D, Fung A, Liu L, Yau H, Potter O, et al.
Mol Cell Proteomics . 2019 Oct; 19(1):11-30. PMID: 31591262
Glycosylation is a topic of intense current interest in the development of biopharmaceuticals because it is related to drug safety and efficacy. This work describes results of an interlaboratory study...
15.
Chatterjee S, Y Lee L, Kawahara R, Abrahams J, Adamczyk B, Anugraham M, et al.
Proteomics . 2019 Aug; 19(21-22):e1900010. PMID: 31419058
While aberrant protein glycosylation is a recognized characteristic of human cancers, advances in glycoanalytics continue to discover new associations between glycoproteins and tumorigenesis. This glycomics-centric study investigates a possible link...
16.
De Oliveira D, Everest-Dass A, Hartley-Tassell L, Day C, Indraratna A, Brouwer S, et al.
FASEB J . 2019 Jul; 33(10):10808-10818. PMID: 31262188
Colonization of the oropharynx is the initial step in Group A (GAS) pharyngeal infection. We have previously reported that the highly virulent M1T1 GAS clone attaches to oral epithelial cells...
17.
Iqbal S, Ghanimi Fard M, Everest-Dass A, Packer N, Parker L
Biochem Soc Trans . 2018 Dec; 47(1):89-100. PMID: 30559272
Glycosylation, the enzymatic process by which glycans are attached to proteins and lipids, is the most abundant and functionally important type of post-translational modification associated with brain development, neurodegenerative disorders,...
18.
Alagesan K, Everest-Dass A, Kolarich D
Adv Exp Med Biol . 2018 Nov; 1104:77-99. PMID: 30484245
Individual monosaccharides can be linked in a variety of different combinations to form complex glycoconjugates. In contrast to DNA and proteins, glycoconjugate synthesis does not follow any template but is...
19.
Tomek M, Maresch D, Windwarder M, Friedrich V, Janesch B, Fuchs K, et al.
Front Microbiol . 2018 Sep; 9:2008. PMID: 30210478
The cell surface of the oral pathogen is heavily glycosylated with a unique, complex decasaccharide that is -glycosidically linked to the bacterium's abundant surface (S-) layer, as well as other...
20.
Cordina N, Sayyadi N, Parker L, Everest-Dass A, Brown L, Packer N
Sci Rep . 2018 Mar; 8(1):4521. PMID: 29540838
Bio-imaging is a key technique in tracking and monitoring important biological processes and fundamental biomolecular interactions, however the interference of background autofluorescence with targeted fluorophores is problematic for many bio-imaging...