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Arne Pfeufer

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Articles 83
Citations 6711
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Recent Articles
1.
Schader J, Haid M, Cecil A, Schoenfeld J, Halle M, Pfeufer A, et al.
Metabolites . 2020 Mar; 10(3). PMID: 32121570
This study compared metabolite shifts induced by training for, participation in, and recovery from a marathon race competition among athletes divided into three groups based on fitness (relative maximum oxygen...
2.
Fredrich B, Schmohl M, Junge O, Gundlach S, Ellinghaus D, Pfeufer A, et al.
PLoS One . 2019 Apr; 14(4):e0215618. PMID: 31022234
Massively parallel DNA sequencing of clinical samples holds great promise for the gene-based diagnosis of human inherited diseases because it allows rapid detection of putatively causative mutations at genome-wide level....
3.
van Setten J, Brody J, Jamshidi Y, Swenson B, Butler A, Campbell H, et al.
Nat Commun . 2018 Jul; 9(1):2904. PMID: 30046033
Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome-wide association study of over 92,000 European-descent...
4.
Eichenlaub M, Pfeufer A, Behrens L, Klauss V, Roettinger M, Brodherr T, et al.
J Cardiovasc Electrophysiol . 2018 Jan; 29(3):365-374. PMID: 29315961
Introduction: Cerebral events (CEs), including silent (SCEs), are a known complication of left atrial catheter ablation (LACA) in patients with atrial fibrillation. The aim of this prospective registry was to...
5.
Wild P, Felix J, Schillert A, Teumer A, Chen M, Leening M, et al.
J Clin Invest . 2017 Apr; 127(5):1798-1812. PMID: 28394258
Background: Understanding the genetic architecture of cardiac structure and function may help to prevent and treat heart disease. This investigation sought to identify common genetic variations associated with inter-individual variability...
6.
Boger C, Gorski M, McMahon G, Xu H, Chang Y, van der Most P, et al.
J Am Soc Nephrol . 2017 Apr; 28(8):2311-2321. PMID: 28360221
Disorders of water balance, an excess or deficit of total body water relative to body electrolyte content, are common and ascertained by plasma hypo- or hypernatremia, respectively. We performed a...
7.
van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano M, et al.
J Am Coll Cardiol . 2016 Sep; 68(13):1435-1448. PMID: 27659466
Background: Myocardial mass is a key determinant of cardiac muscle function and hypertrophy. Myocardial depolarization leading to cardiac muscle contraction is reflected by the amplitude and duration of the QRS...
8.
Ortiz-Bonnin B, Rinne S, Moss R, Streit A, Scharf M, Richter K, et al.
Pflugers Arch . 2016 Jun; 468(8):1375-87. PMID: 27287068
SCN5A encodes for the α-subunit of the cardiac voltage-gated sodium channel Nav1.5. Gain-of-function mutations in SCN5A are related to congenital long QT syndrome (LQTS3) characterized by delayed cardiac repolarization, leading...
9.
Fard D, Laer K, Rothamel T, Schurmann P, Arnold M, Cohen M, et al.
Int J Legal Med . 2016 Mar; 130(4):1025-1033. PMID: 26975745
Background: Sudden infant death syndrome (SIDS) causes early infant death with an incidence between 0.5 and 2.5 cases among 1000 live births. Besides central sleep apnea and thermal dysregulation, infections...
10.
Butzke B, Oduncu F, Severin F, Pfeufer A, Heinemann V, Giessen-Jung C, et al.
Acta Oncol . 2015 Jun; 55(3):318-28. PMID: 26098842
Background: The evidence concerning the cost-effectiveness of UGT1A1*28 genotyping is ambiguous and does not allow drawing valid conclusions for Germany. This study evaluates the cost-effectiveness of UGT1A1 genotyping in patients...