Arijit Dutta
Overview
Explore the profile of Arijit Dutta including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
197
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0
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Recent Articles
1.
Olazabal-Herrero A, He B, Kwon Y, Gupta A, Dutta A, Huang Y, et al.
Cell Rep
. 2024 Jan;
43(1):113610.
PMID: 38165804
Fanconi anemia (FA) is characterized by congenital abnormalities, bone marrow failure, and cancer susceptibility. The central FA protein complex FANCI/FANCD2 (ID2) is activated by monoubiquitination and recruits DNA repair proteins...
2.
Chakraborty A, Dutta A, Dettori L, Daoud R, Li J, Gonzalez L, et al.
J Biol Chem
. 2023 Dec;
300(1):105572.
PMID: 38110032
Mutations in, or deficiency of, fragile X messenger ribonucleoprotein (FMRP) is responsible for the Fragile X syndrome (FXS), the most common cause for inherited intellectual disability. FMRP is a nucleocytoplasmic...
3.
Jaiswal A, Dutta A, Srinivasan G, Yuan Y, Zhou D, Shaheen M, et al.
Nucleic Acids Res
. 2023 Nov;
51(22):12224-12241.
PMID: 37953292
BRCA1-deficient cells have increased IRE1 RNase, which degrades multiple microRNAs. Reconstituting expression of one of these, miR-4638-5p, resulted in synthetic lethality in BRCA1-deficient cancer cells. We found that miR-4638-5p represses...
4.
Camino L, Dutta A, Barroso S, Perez-Calero C, Katz J, Garcia-Rubio M, et al.
Mol Cell
. 2023 Oct;
83(20):3707-3719.e5.
PMID: 37827159
R-loops, which consist of a DNA-RNA hybrid and a displaced DNA strand, are known to threaten genome integrity. To counteract this, different mechanisms suppress R-loop accumulation by either preventing the...
5.
Dutta A, Mitra J, Hegde P, Mitra S, Hegde M
Methods Mol Biol
. 2023 Aug;
2701:173-182.
PMID: 37574482
DNA double-strand breaks (DSBs) are the most lethal genomic lesions that are induced endogenously during physiological reactions as well as by external stimuli and genotoxicants. DSBs are repaired in mammalian...
6.
Jaiswal A, Kim H, Scharer O, Sharma N, Williamson E, Srinivasan G, et al.
NAR Cancer
. 2023 Jan;
5(1):zcac044.
PMID: 36683914
Unrepaired oxidatively-stressed replication forks can lead to chromosomal instability and neoplastic transformation or cell death. To meet these challenges cells have evolved a robust mechanism to repair oxidative genomic DNA...
7.
Dutta A, Kwon Y, Sung P
Methods Mol Biol
. 2022 Jun;
2528:305-316.
PMID: 35704200
R-loops, three-stranded RNA-DNA hybrids that arise mostly during transcription, could cause genomic instability via distinct routes. Detection of genomic RNA-DNA hybrids via immunofluorescence and RNA-DNA hybrid immunoprecipitation techniques have facilitated...
8.
Bowen S, Dutta A, Rytel K, Abramowitch S, Rogers R, Moalli P
Int Urogynecol J
. 2022 Apr;
33(6):1649-1657.
PMID: 35394140
Introduction And Hypothesis: We present a 3D computational approach for automated clitoral measurements. We hypothesized that computationally derived measurements would be comparable and less variable than reported manual measures. Methods:...
9.
Gomez-Gonzalez B, Dutta A, Feng W
Front Mol Biosci
. 2022 Feb;
9:848217.
PMID: 35224000
No abstract available.
10.
Dettori L, Torrejon D, Chakraborty A, Dutta A, Mohamed M, Papp C, et al.
Front Mol Biosci
. 2021 Jun;
8:691694.
PMID: 34179096
R-loops are non-canonical, three-stranded nucleic acid structures composed of a DNA:RNA hybrid, a displaced single-stranded (ss)DNA, and a trailing ssRNA overhang. R-loops perform critical biological functions under both normal and...