Aparna Bhaduri
Overview
Explore the profile of Aparna Bhaduri including associated specialties, affiliations and a list of published articles.
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67
Citations
5794
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Recent Articles
1.
He L, Azizad D, Bhat K, Ioannidis A, Hoffmann C, Arambula E, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(9):e2415557122.
PMID: 40009641
Glioblastoma (GBM) is the deadliest brain cancer in adults, and all patients succumb to the tumor. While surgery followed by chemoradiotherapy delays disease progression, these treatments do not lead to...
2.
Adameyko I, Bakken T, Bhaduri A, Chhatbar C, Filbin M, Gate D, et al.
Nat Neurosci
. 2024 Dec;
27(12):2278-2291.
PMID: 39627588
Single-cell and single-nucleus genomic approaches can provide unbiased and multimodal insights. Here, we discuss what constitutes a molecular cell atlas and how to leverage single-cell omics data to generate hypotheses...
3.
Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis
Mirchia K, Choudhury A, Joseph T, Birrueta J, Phillips J, Bhaduri A, et al.
Neuro Oncol
. 2024 Aug;
27(1):155-166.
PMID: 39207122
Background: Meningeal solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that are associated with local recurrence and hematogenous metastasis. The cell states and spatial transcriptomic architecture underlying the unique clinical...
4.
Fazzari E, Azizad D, Yu K, Ge W, Li M, Nano P, et al.
bioRxiv
. 2024 Aug;
PMID: 39091877
Glioblastoma (GBM) is the deadliest form of primary brain tumor with limited treatment options. Recent studies have profiled GBM tumor heterogeneity, revealing numerous axes of variation that explain the molecular...
5.
Diaz-Salazar C, Krzisch M, Yoo J, Nano P, Bhaduri A, Jaenisch R, et al.
bioRxiv
. 2024 Jul;
PMID: 38979266
Microglia play key roles in shaping synaptic connectivity during neural circuits development. Whether microglia display human-specific features of structural and functional maturation is currently unknown. We show that the ancestral...
6.
Visvanathan A, Saulnier O, Chen C, Haldipur P, Orisme W, Delaidelli A, et al.
Cell
. 2024 Jul;
187(17):4733-4750.e26.
PMID: 38971152
We identify a population of Protogenin-positive (PRTG) MYC NESTIN stem cells in the four-week-old human embryonic hindbrain that subsequently localizes to the ventricular zone of the rhombic lip (RL). Oncogenic...
7.
8.
He L, Azizad D, Bhat K, Ioannidis A, Hoffmann C, Arambula E, et al.
bioRxiv
. 2024 May;
PMID: 38798647
Glioblastoma is the deadliest brain cancer in adults and almost all patients succumb to the tumor. While surgery followed by chemo-radiotherapy significantly delays disease progression, these treatments do not lead...
9.
Choudhury A, Cady M, Lucas C, Najem H, Phillips J, Palikuqi B, et al.
Cancer Discov
. 2024 May;
14(10):1823-1837.
PMID: 38742767
Meningiomas are the most common primary intracranial tumors. Treatments for patients with meningiomas are limited to surgery and radiotherapy, and systemic therapies remain ineffective or experimental. Resistance to radiotherapy is...
10.
Shin D, Kim C, Ross J, Hennick K, Wu S, Paranjape N, et al.
Cell Stem Cell
. 2024 Feb;
31(3):421-432.e8.
PMID: 38382530
Thalamic dysfunction has been implicated in multiple psychiatric disorders. We sought to study the mechanisms by which abnormalities emerge in the context of the 22q11.2 microdeletion, which confers significant genetic...