Patricia R Nano
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Explore the profile of Patricia R Nano including associated specialties, affiliations and a list of published articles.
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8
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29
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Recent Articles
1.
Fazzari E, Azizad D, Yu K, Ge W, Li M, Nano P, et al.
bioRxiv
. 2024 Aug;
PMID: 39091877
Glioblastoma (GBM) is the deadliest form of primary brain tumor with limited treatment options. Recent studies have profiled GBM tumor heterogeneity, revealing numerous axes of variation that explain the molecular...
2.
Diaz-Salazar C, Krzisch M, Yoo J, Nano P, Bhaduri A, Jaenisch R, et al.
bioRxiv
. 2024 Jul;
PMID: 38979266
Microglia play key roles in shaping synaptic connectivity during neural circuits development. Whether microglia display human-specific features of structural and functional maturation is currently unknown. We show that the ancestral...
3.
Nano P, Fazzari E, Azizad D, Nguyen C, Wang S, Kan R, et al.
bioRxiv
. 2023 Sep;
PMID: 37745597
Human brain development requires the generation of hundreds of diverse cell types, a process targeted by recent single-cell transcriptomic profiling efforts. Through a meta-analysis of seven of these published datasets,...
4.
Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways
Pun M, Pratt D, Nano P, Joshi P, Jiang L, Englinger B, et al.
Acta Neuropathol Commun
. 2023 Feb;
11(1):25.
PMID: 36759899
Globally decreased histone 3, lysine 27 tri-methylation (H3K27me3) is a hallmark of H3K27-altered diffuse midline gliomas (DMGs) and group-A posterior fossa ependymomas (PFAs). H3K27-altered DMGs are largely characterized by lysine-to-methionine...
5.
Nano P, Bhaduri A
Dev Neurobiol
. 2022 Jun;
82(5):408-427.
PMID: 35644985
Compared with that of even the closest primates, the human cortex displays a high degree of specialization and expansion that largely emerges developmentally. Although decades of research in the mouse...
6.
Nano P, Bhaduri A
Neuron
. 2022 Feb;
110(3):353-355.
PMID: 35114104
In this issue of Neuron, Franjic et al. (2022) use a single-nuclei RNA sequencing approach that identified signatures of adult neurogenesis in mouse, pig, and macaque dentate gyrus, but not...
7.
Nano P, Nguyen C, Mil J, Bhaduri A
Front Neural Circuits
. 2021 Dec;
15:788560.
PMID: 34955761
The cerebral cortex derives its cognitive power from a modular network of specialized areas processing a multitude of information. The assembly and organization of these regions is vital for human...
8.
Nano P, Johnson T, Kudo T, Mooney N, Ni J, Demeter J, et al.
PLoS One
. 2021 May;
16(5):e0251684.
PMID: 33999959
ARHGAP36 is an atypical Rho GTPase-activating protein (GAP) family member that drives both spinal cord development and tumorigenesis, acting in part through an N-terminal motif that suppresses protein kinase A...