Anusha Thadi
Overview
Explore the profile of Anusha Thadi including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
212
Followers
0
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Recent Articles
1.
Xu J, Chen C, Sussman J, Yoshimura S, Vincent T, Polonen P, et al.
Nat Cancer
. 2024 Nov;
6(1):102-122.
PMID: 39587259
Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to curing T cell acute lymphoblastic leukemia (T-ALL). While tumor heterogeneity has been implicated in treatment failure, the...
2.
Grossmann L, Chen C, Uzun Y, Thadi A, Wolpaw A, Louault K, et al.
Cancer Discov
. 2024 Jul;
14(12):2387-2406.
PMID: 39083807
Relapse rates in high-risk neuroblastoma remain exceedingly high. The malignant cells that are responsible for relapse have not been identified, and mechanisms of therapy resistance remain poorly understood. In this...
3.
Bandyopadhyay S, Duffy M, Ahn K, Sussman J, Pang M, Smith D, et al.
Cell
. 2024 May;
187(12):3120-3140.e29.
PMID: 38714197
Non-hematopoietic cells are essential contributors to hematopoiesis. However, heterogeneity and spatial organization of these cells in human bone marrow remain largely uncharacterized. We used single-cell RNA sequencing (scRNA-seq) to profile...
4.
Bandyopadhyay S, Duffy M, Ahn K, Pang M, Smith D, Duncan G, et al.
bioRxiv
. 2024 Apr;
PMID: 38559168
The bone marrow is the organ responsible for blood production. Diverse non-hematopoietic cells contribute essentially to hematopoiesis. However, these cells and their spatial organization remain largely uncharacterized as they have...
5.
Sussman J, Oldridge D, Yu W, Chen C, Zellmer A, Rong J, et al.
bioRxiv
. 2024 Mar;
PMID: 38496580
Pediatric high-grade glioma (pHGG) is an incurable central nervous system malignancy that is a leading cause of pediatric cancer death. While pHGG shares many similarities to adult glioma, it is...
6.
Tan K, Xu J, Chen C, Vincent T, Polonen P, Hu J, et al.
Res Sq
. 2023 Nov;
PMID: 37961674
Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to cure in T-cell Acute Lymphoblastic Leukemia (T-ALL). Biomarker guided risk stratification and targeted therapy have the potential...
7.
Morral C, Ghinnagow R, Karakasheva T, Zhou Y, Thadi A, Li N, et al.
Bio Protoc
. 2023 Sep;
13(18):e4825.
PMID: 37753470
Inflammation of the gastrointestinal tract is a prevalent pathology in diseases such as inflammatory bowel disease (IBD). Currently, there are no therapies to prevent IBD, and available therapies to treat...
8.
Sarafraz-Yazdi E, Mumin S, Cheung D, Fridman D, Lin B, Wong L, et al.
Biomedicines
. 2022 May;
10(5).
PMID: 35625682
PNC-27, a 32-residue peptide that contains an HDM-2 binding domain and a cell-penetrating peptide (CPP) leader sequence kills cancer, but not normal, cells by binding to HDM-2 associated with the...
9.
Thadi A, Morano W, Khalili M, Babcock B, Shaikh M, Foster D, et al.
Anticancer Res
. 2021 Jan;
41(1):27-42.
PMID: 33419797
Background/aim: We have tested whether the anticancer peptide, PNC-27, that kills cancer cells but not normal cells by binding to cancer cell membrane HDM-2 forming pores, kills CD44+ colon cancer...
10.
Thadi A, Gleeson E, Khalili M, Shaikh M, Goldstein E, Morano W, et al.
Ann Clin Lab Sci
. 2020 Oct;
50(5):611-624.
PMID: 33067207
Objective: Patients with epithelial ovarian cancers experience the highest fatality rates among all gynecological malignancies which require development of novel treatment strategies. Tumor cell necrosis was previously reported in a...