Anu Mahadevan
Overview
Explore the profile of Anu Mahadevan including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
995
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Recent Articles
1.
Pelleg A, Sirtori E, Rolland J, Mahadevan A
Purinergic Signal
. 2023 Mar;
19(3):467-479.
PMID: 36944825
Extracellular adenosine 5'-triphosphate (ATP) acts as an autocrine and paracrine agent, the actions of which on affected cells are mediated by P2 receptors (P2R), which include trans cell-membrane cationic channels...
2.
Muldoon P, Akinola L, Schlosburg J, Lichtman A, Sim-Selley L, Mahadevan A, et al.
Neuropharmacology
. 2020 Jun;
176:108170.
PMID: 32479813
Nicotine, the primary psychoactive component in tobacco, plays a major role in the initiation and maintenance of tobacco dependence and addiction, a leading cause of preventable death worldwide. An essential...
3.
Crowe M, Leishman E, Banks M, Gujjar R, Mahadevan A, Bradshaw H, et al.
Br J Pharmacol
. 2014 Nov;
172(7):1700-12.
PMID: 25393148
Background And Purpose: Neuropathic pain is commonly treated with GABA analogues, steroids or non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs inhibit one or more COX isozymes but chronic COX inhibition paradoxically increases...
4.
Murase R, Kawamura R, Singer E, Pakdel A, Sarma P, Judkins J, et al.
Br J Pharmacol
. 2014 Jun;
171(19):4464-77.
PMID: 24910342
Background And Purpose: The psychoactive cannabinoid Δ(9) -tetrahydrocannabinol (THC) and the non-psychoactive cannabinoid cannabidiol (CBD) can both reduce cancer progression, each through distinct anti-tumour pathways. Our goal was to discover...
5.
Zhang M, Mahadevan A, Amere M, Li H, Ganea D, Tuma R
Transl Stroke Res
. 2013 Dec;
3(3):348-56.
PMID: 24323810
We reported previously that both a cannabinoid receptor 2 (CB2R) agonist and a cannabinoid receptor 1 (CB1R) antagonist were protective in the treatment of transient middle cerebral artery occlusion/reperfusion injury...
6.
Bisogno T, Mahadevan A, Coccurello R, Chang J, Allara M, Chen Y, et al.
Br J Pharmacol
. 2012 Oct;
169(4):784-93.
PMID: 23072382
Background And Purpose: The development of potent and selective inhibitors of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) via DAG lipases (DAGL) α and β is just starting to be...
7.
Wiley J, Marusich J, Zhang Y, Fulp A, Maitra R, Thomas B, et al.
Eur J Pharmacol
. 2012 Sep;
695(1-3):62-70.
PMID: 22975289
Obesity contributes to a multitude of serious health problems. Given the demonstrated role of the endogenous cannabinoid system in appetite regulation, the purpose of the present study was to evaluate...
8.
Ghosh S, Wise L, Chen Y, Gujjar R, Mahadevan A, Cravatt B, et al.
Life Sci
. 2012 Jul;
92(8-9):498-505.
PMID: 22749865
Aim: The present study tested whether the selective monoacylglycerol lipase (MAGL) inhibitor JZL184 would reduce allodynia and paw edema in the carrageenan test. Main Methods: The anti-edematous and anti-allodynic effects...
9.
Ramirez S, Hasko J, Skuba A, Fan S, Dykstra H, McCormick R, et al.
J Neurosci
. 2012 Mar;
32(12):4004-16.
PMID: 22442067
Previous studies have shown that modulation of the receptor-mediated cannabinoid system during neuroinflammation can produce potent neuroprotective and anti-inflammatory effects. However, in this context, little is known about how selective...
10.
Kinsey S, Nomura D, ONeal S, Long J, Mahadevan A, Cravatt B, et al.
J Pharmacol Exp Ther
. 2011 Jun;
338(3):795-802.
PMID: 21659471
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used analgesics, but can cause gastric and esophageal hemorrhages, erosion, and ulceration. The endogenous cannabinoid (endocannabinoid; eCB) system possesses several potential targets to reduce...